DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hoxb3 and Awh

DIOPT Version :9

Sequence 1:	NP_001073338.1	Gene:	Hoxb3 / 15410	MGIID:	96184	Length:	433	Species:	Mus musculus
Sequence 2:	NP_001261379.1	Gene:	Awh / 38451	FlyBaseID:	FBgn0013751	Length:	287	Species:	Drosophila melanogaster

Alignment Length:	194	Identity:	46/194 - (23%)
Similarity:	70/194 - (36%)	Gaps:	47/194 - (24%)

- Green bases have known domain annotations that are detailed below.

Mouse   167 GGGSSGGGGGGGGGGDKSPPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLS 231
            ||.:|...|..|.|..||     .:||.||.:|..||..|:..|..:..........:|::..||
  Fly   129 GGTTSSDEGCDGDGYHKS-----KTKRVRTTFTEEQLQVLQANFQIDSNPDGQDLERIASVTGLS 188

Mouse   232 ERQIKIWFQNRRMKYKKDQKAKGLASSSGGPSPAGSPPQPMQSTAGFMNALHSMTPSYDSPSPPA 296
            :|..::||||.|.:.||.                                :|:.......|...:
  Fly   189 KRVTQVWFQNSRARQKKH--------------------------------IHAGKNKIREPEGSS 221

Mouse   297 FGKGHQN---AYALPSNYQPPLKGCGAPQKYPPTPASEYEPHVLQANGGAYGTPT----MQGSP 353
            |.: |.|   .|:..:|.|.|:...|:.....||..|..:.  |..:...:..|:    .|.||
  Fly   222 FAR-HINLQLTYSFQNNAQNPMHLNGSKAGLYPTHESSMDE--LSQDSSVHCMPSEVXLEQSSP 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hoxb3	NP_001073338.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	63..124
		Antp-type hexapeptide	129..134
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	136..195		10/27 (37%)
		Homeobox	195..248	CDD:365835	16/52 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	249..276		0/26 (0%)
		DUF4074	369..431	CDD:372548
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	389..433
Awh	NP_001261379.1	LIM1_AWH	8..61	CDD:188759
		LIM2_AWH	69..123	CDD:188765
		Homeobox	152..204	CDD:278475	16/51 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910