DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hoxb3 and PHDP

DIOPT Version :9

Sequence 1:	NP_001073338.1	Gene:	Hoxb3 / 15410	MGIID:	96184	Length:	433	Species:	Mus musculus
Sequence 2:	NP_523834.1	Gene:	PHDP / 37788	FlyBaseID:	FBgn0025334	Length:	220	Species:	Drosophila melanogaster

Alignment Length:	131	Identity:	44/131 - (33%)
Similarity:	61/131 - (46%)	Gaps:	36/131 - (27%)

- Green bases have known domain annotations that are detailed below.

Mouse   182 DKSPPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKY 246
            |||     ..:|.||.:||.||.||||.|....|.....|.|:|:.|:|:|.::::||||||.|:
  Fly   108 DKS-----KQRRIRTTFTSNQLNELEKIFLETHYPDIYTREEIASKLHLTEARVQVWFQNRRAKF 167

Mouse   247 KKDQK-----AKGLASS-SGGPSP-AGSPPQPMQSTAGFMNALHSMTPSYDSPSPPAFGKGHQNA 304
            :|.::     .|..:|. .|..:| |||                    .|..||.    ||.||.
  Fly   168 RKQERHAIYIMKDKSSKLDGRKNPVAGS--------------------KYLGPSL----KGPQNG 208

Mouse   305 Y 305
            :
  Fly   209 H 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hoxb3	NP_001073338.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	63..124
		Antp-type hexapeptide	129..134
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	136..195		4/12 (33%)
		Homeobox	195..248	CDD:365835	25/52 (48%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	249..276		7/33 (21%)
		DUF4074	369..431	CDD:372548
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	389..433
PHDP	NP_523834.1	Homeobox	116..168	CDD:278475	25/51 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910