Protein Alignment Hoxb3 and scro

DIOPT Version :10

• Sequence 1: NP_034588.2
• Gene: Hoxb3 / 15410
• MGIID: 96184
• Length: 433
• Species: Mus musculus
• Sequence 2: NP_001015473.1
• Gene: scro / 3355151
• FlyBaseID: FBgn0287186
• Length: 468
• Species: Drosophila melanogaster
• Alignment Length: 438
• Identity: 103/438 - (23%)
• Similarity: 155/438 - (35%)
• Gaps: 122/438 - (27%)

Mouse    42 HLEGDYQRSACSLQSLGNAAPHA------------KSKELNGSCMRPGLAPEPLPAPPGSPPPSA 94
            ||:..:.:...:|.:..::.|.:            :..||||:      .|.|..:...|...::
  Fly    95 HLQNLHSQHQSTLFNSNHSTPFSVTDILSPIEESYRKLELNGN------PPSPFRSNSSSSSINS 153

Mouse    95 APTSTTSNSNNGGGPSKSG--------PPKCGAGSNSTLT------KQIFPWMKESRQTSK---- 141
            ..|.|||...|   |...|        ...||...|.:|.      :....|...:....:
  Fly   154 PGTLTTSTMAN---PYAMGTLYHSPGVQTYCGPTDNLSLAGHYTDMRNSASWYGSTANDPRFAIS 215

Mouse   142 --LKNSSPGTAEGCGGGGGGGGGGGGGGGGSSGGGGGGGGGGDKSP---PGSAASKRARTAYTSA 201
              :.:|:.||....|                :..|.......|..|   |.:...|| |..:|.|
  Fly   216 RLMSSSASGTMSHMG----------------NMSGLAACSVSDSKPLQFPLAQRRKR-RVLFTQA 263

Mouse   202 QLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAKGLASSSGGPSPAG 266
            |:.|||:.|...|||..|.|..:|:|::|:..|:||||||.|.|.|:..|.|.:|..:....||.
  Fly   264 QVYELERRFKQQRYLSAPEREHLASLIHLTPTQVKIWFQNHRYKCKRQAKEKAMAEQNQHNQPAS 328

Mouse   267 SPPQ---PM-----QSTAGFMNALHSMTPSYDSPSPPA--------FGKGHQNAYALPSNYQPPL 315
            ||.:   |:     :..:|  |...|.:..:.:.|..|        .|..:....::.:|....|
  Fly   329 SPRRVAVPVLVKDGKPCSG--NNSSSQSQQHGTNSTSAGNNTGSANNGNANSGIVSVTANVSGGL 391

Mouse   316 K---GCGAPQKYPPTPASEYEPHVLQANGGAYGTPTMQGSPVYVGGGGYADPLPPPAGPSLYGLN 377
            .   | .||..:.|..:|.     |.|   :|||         |||...| .|..|...:|.. |
  Fly   392 NLITG-DAPNSHSPDTSSS-----LLA---SYGT---------VGGSNVA-MLQQPCNNTLMS-N 436

Mouse   378 HL--SHHPSGNLDYNGAAPMGPNQHHGPCDPHPTYTDLSSHHAPPQGR 423
            .|  ::....|...||        |...|          ..:.|.|||
  Fly   437 SLAMAYRNQNNFISNG--------HQQQC----------GGYLPLQGR 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hoxb3	NP_034588.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..124		17/80 (21%)
		Antp-type hexapeptide	129..134		1/4 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	136..195		10/67 (15%)
		Homeodomain	192..248	CDD:459649	27/55 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	249..276		8/34 (24%)
		DUF4074	369..431	CDD:463833	12/57 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	389..433		8/35 (23%)
scro	NP_001015473.1	Homeodomain	254..310	CDD:459649	27/56 (48%)