DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hoxb3 and CG32532

DIOPT Version :9

Sequence 1:	NP_001073338.1	Gene:	Hoxb3 / 15410	MGIID:	96184	Length:	433	Species:	Mus musculus
Sequence 2:	NP_608318.5	Gene:	CG32532 / 32943	FlyBaseID:	FBgn0052532	Length:	688	Species:	Drosophila melanogaster

Alignment Length:	329	Identity:	78/329 - (23%)
Similarity:	115/329 - (34%)	Gaps:	100/329 - (30%)

- Green bases have known domain annotations that are detailed below.

Mouse    93 SAAPTSTTSNSNNGGGPSKSGPPKCGAGSNSTLT-----KQIFPWMKESRQTSKLKNSSPGTAEG 152
            |..||....:|::...|:.:.|.:.   |:.|::     |::.|.......|.....:|||:
  Fly   429 SGLPTPGMDSSSHHHTPAHTPPSRL---SDHTISAEGAFKKLKPEPNSGLSTVSAGITSPGS--- 487

Mouse   153 CGGGGGGGGGGGGGGGGSSGGGGGGGGGGDKSPPGSAASKRARTAYTSAQLVELEKEF---HFNR 214
                           |.||.....|......|.| :.|.:|.||.:|..||.|||..|   |:..
  Fly   488 ---------------GLSSLSQHAGHTPTTASCP-TPARRRHRTTFTQEQLAELEAAFAKSHYPD 536

Mouse   215 YLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQK--AKGLASSSGGPSPAGSPPQPMQSTAG 277
            ..||.   |:|....|:|.:|::||||||.||:|.:|  .|.||            |..:.|..|
  Fly   537 IYCRE---ELARTTKLNEARIQVWFQNRRAKYRKQEKQLQKALA------------PSVIPSCNG 586

Mouse   278 FMNALHSMTPSYDSPSPPAFGKGHQNAYALPSNYQPPLKGCGAPQKYP-PTPASEYEPHVLQANG 341
            .|..:                    ..|::...|||          || ....:.|...:.|...
  Fly   587 MMRNI--------------------QGYSVSRGYQP----------YPHHNTMNRYPQDLFQMGA 621

Mouse   342 GAYGTPTMQGSPVYVGGGGYADPLPPPAGPSLYGLN---------------HLSHHPSGNLDYNG 391
            .:|...|...|..:....|.........| ..:|::               :.||||      |.
  Fly   622 SSYPGMTQPFSMAHSTNMGSVGVRQDSMG-EFHGMSPEDEWYNKSLSALRMNSSHHP------NL 679

Mouse   392 AAPM 395
            :|||
  Fly   680 SAPM 683

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hoxb3	NP_001073338.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	63..124		7/30 (23%)
		Antp-type hexapeptide	129..134		1/4 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	136..195		12/58 (21%)
		Homeobox	195..248	CDD:365835	25/55 (45%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	249..276		6/28 (21%)
		DUF4074	369..431	CDD:372548	10/42 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	389..433		4/7 (57%)
CG32532	NP_608318.5	Homeobox	513..566	CDD:278475	24/55 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910