DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hoxb3 and OdsH

DIOPT Version :9

Sequence 1:	NP_001073338.1	Gene:	Hoxb3 / 15410	MGIID:	96184	Length:	433	Species:	Mus musculus
Sequence 2:	NP_523389.3	Gene:	OdsH / 32758	FlyBaseID:	FBgn0026058	Length:	382	Species:	Drosophila melanogaster

Alignment Length:	282	Identity:	67/282 - (23%)
Similarity:	98/282 - (34%)	Gaps:	73/282 - (25%)

- Green bases have known domain annotations that are detailed below.

Mouse   169 GSSGG--------GGGGGGGGDKSPPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMA 225
            |||.|        .|.....|......|:..:|.||.:.|.||.|||:.|..:.|.....|..:|
  Fly   128 GSSRGIKQDPLSDEGADSNLGQNDCTESSKKRRGRTNFNSWQLRELERVFQGSHYPDIFMREALA 192

Mouse   226 NLLNLSERQIKIWFQNRRMKYKKDQ---KAKGLASSSGGPSPAGSPPQPMQSTAGFMNALHS--M 285
            ..|:|.|.:|.:||||||.|::|.:   |..|..:.:..|......|.|:........|..|  |
  Fly   193 TKLDLMEGRIAVWFQNRRAKWRKQEHTKKGPGRPAHNAHPQSCSGDPIPLSELRARELAQRSKRM 257

Mouse   286 TPSYDSPSPPAFGKGHQNAYA-LPSNYQPPLKGCGAPQKYPPTPASEYEPHVLQANGGAYGTPTM 349
            ..:.|..:.....||.:..|| |.:.|.                |:..|..|.:.|
  Fly   258 KKAIDRQAKKLQDKGLEVDYARLEAEYL----------------AAHQENGVDENN--------- 297

Mouse   350 QGSPVYVGGGGYADPLPPPAGPSLYGLNHLSHHPSGNLDYNGAAP---MGPNQHHGPCDPH---- 407
                 ::...||.|.                     ::|..|..|   .|.:..|..|...
  Fly   298 -----WLDDDGYDDL---------------------HIDVVGVEPEYVTGDSLDHSFCSSRTYQT 336

Mouse   408 -PTYTDLSSHHAPPQGRIQEAP 428
             .|.::|.|:....|||::..|
  Fly   337 KSTSSELDSNDMGLQGRVETPP 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hoxb3	NP_001073338.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	63..124
		Antp-type hexapeptide	129..134
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	136..195		8/33 (24%)
		Homeobox	195..248	CDD:365835	23/52 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	249..276		5/29 (17%)
		DUF4074	369..431	CDD:372548	13/68 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	389..433		12/48 (25%)
OdsH	NP_523389.3	Homeobox	162..214	CDD:278475	23/51 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910