Protein Alignment Hoxb1 and HGTX

DIOPT Version :10

• Sequence 1: XP_006532343.1
• Gene: Hoxb1 / 15407
• MGIID: 96182
• Length: 330
• Species: Mus musculus
• Sequence 2: NP_001368954.1
• Gene: HGTX / 53446
• FlyBaseID: FBgn0040318
• Length: 587
• Species: Drosophila melanogaster
• Alignment Length: 357
• Identity: 82/357 - (22%)
• Similarity: 126/357 - (35%)
• Gaps: 104/357 - (29%)

Mouse    13 PLC--NRGPSAYSAPTSF--PPCSAPAVDSYAGESRYGGGLPSSALQQNSGYPVQQPPSSLGVSF 73
            |.|  |.....:..|.||  ||.:  |:.|...|.: |.|:..|:...|            |:|:
  Fly   275 PGCHNNNNHMDHKLPLSFLGPPLA--ALHSMTTEMK-GQGVGGSSASAN------------GLSY 324

Mouse    74 PSPAPSGYAPAACNPSYGP-SQYYSVGQSEGDGSYFHPSSYGAQLGGLPDSYGAGGVGSGPYPPP 137
                           |:.| |...|...|.|..|....::......|.|:.:|...:.|  .|||
  Fly   325 ---------------SHSPNSHLISDRGSGGSSSSSSTTTTNTNSQGAPNPHGIDTILS--KPPP 372

Mouse   138 QPPYGTEQ-----------TATFASAYDLLSEDKESPCSSEPSTLTPRT-FDWMKVK---RNPPK 187
            ....|...           .|..|.....||:.:.:|..:....:..|| ..|..::   .| |.
  Fly   373 VTSAGLSALTGAGIPRFSIAAAAAGMAQYLSQSQGAPLKTHAGHIVDRTHLYWPGLQGLVAN-PI 436

Mouse   188 TGRAQRSHFLS--LARAYTEGPEPGLHSFLQLLLLAAKVSELGLGAPGGLRTNFTTRQLTELEKE 250
            ..|.:.|:.:|  |::::...|                 |....|.....|..|:.:|:..|||.
  Fly   437 AWRERLSNTMSANLSQSHQHHP-----------------SNDKDGKKKHTRPTFSGQQIFALEKT 484

Mouse   251 FHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQKKR-----------------EREG---- 294
            |...|||:...|.::|..|.::|:|||:||||||.|.:||                 :.:|
  Fly   485 FEQTKYLAGPERAKLAYALGMSESQVKVWFQNRRTKWRKRHAAEMATAKRKQDDMGGDNDGDCSE 549

Mouse   295 -----------GRMPAGPPGCPKEAAGDASDQ 315
                       |..||....|...::|.:..|
  Fly   550 TMDSDNESLDMGESPAQNKRCRSNSSGSSQQQ 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hoxb1	XP_006532343.1	Homeodomain	236..289	CDD:459649	24/52 (46%)
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709	32/144 (22%)
		Homeodomain	465..523	CDD:459649	24/57 (42%)