Protein Alignment Hoxb1 and cad

DIOPT Version :10

• Sequence 1: XP_006532343.1
• Gene: Hoxb1 / 15407
• MGIID: 96182
• Length: 330
• Species: Mus musculus
• Sequence 2: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Alignment Length: 353
• Identity: 102/353 - (28%)
• Similarity: 138/353 - (39%)
• Gaps: 122/353 - (34%)

Mouse     1 MDYNRMSSFLEYPLCNRGPSAYSAPTSFPPCSAPAVDSYAGESRYGGGLPSSA---LQQNSGYPV 62
            |.||....|       ...:|.||.....|.|:.| |::.      ..:|:||   :||:..:..
  Fly    64 MYYNSHHMF-------HSAAAASAGEWHSPASSTA-DNFV------QNVPTSAHQLMQQHHHHHA 114

Mouse    63 QQPPSSLGVSFPSPAPSGYAPAA-----CNPSYGPSQYYSVGQSEGDGSYFHPSSYGAQLGGLPD 122
            ....||......|   ||.||.|     .|.|.|      ||.:.|.|.          :||..|
  Fly   115 HASSSSASSGSSS---SGGAPGAPQLNETNSSIG------VGGAGGGGG----------VGGATD 160

Mouse   123 SYGAGGVGSGPYPP----------PQPPY---GTEQTA----TFAS------AYDLL-------- 156
                ||.||.  ||          |.||.   |:|.::    |.||      |:.|.
  Fly   161 ----GGPGSA--PPNHQQHIAEGLPSPPITVSGSEISSPGAPTSASSPHHHLAHHLSAVANNNNN 219

Mouse   157 -SEDKESPC-------------SSEPSTLTPRTFDWMKVKRNPPKTGRAQRSHFLSLARAYTEGP 207
             :.:..||.             ::..|...|..|||||   .|                ||...|
  Fly   220 NNNNNNSPSTHNNNNNNNSVSNNNRTSPSKPPYFDWMK---KP----------------AYPAQP 265

Mouse   208 EPGLHSFLQLLLLAAKVSELGLGAPGGLRTN------FTTRQLTELEKEFHFNKYLSRARRVEIA 266
            :|.|.|...|    ..:|:| |.|.|..||.      :|..|..|||||:..::|::..|:.|:|
  Fly   266 QPDLSSSPNL----EDLSDL-LDASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELA 325

Mouse   267 ATLELNETQVKIWFQNRRMKQKKREREG 294
            .||.|:|.||||||||||.|::|:.::|
  Fly   326 QTLSLSERQVKIWFQNRRAKERKQNKKG 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hoxb1	XP_006532343.1	Homeodomain	236..289	CDD:459649	28/58 (48%)
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	26/54 (48%)