DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hoxa7 and Dfd

DIOPT Version :9

Sequence 1:	NP_034585.1	Gene:	Hoxa7 / 15404	MGIID:	96179	Length:	229	Species:	Mus musculus
Sequence 2:	NP_477201.1	Gene:	Dfd / 40832	FlyBaseID:	FBgn0000439	Length:	586	Species:	Drosophila melanogaster

Alignment Length:	335	Identity:	97/335 - (28%)
Similarity:	142/335 - (42%)	Gaps:	116/335 - (34%)

- Green bases have known domain annotations that are detailed below.

Mouse     2 SSSYYVNALFSKYTAGASLFQNAEPTS----CSFAPNSQRSGYGPGAGAF--ASTVPGLYNVNSP 60
            |..|||:......:|||   .:::||:    .:..||:...|.|.|:||.  ...|.|..|.
  Fly   151 SLGYYVHHAPEFISAGA---VHSDPTNGYGPAANVPNTSNGGGGGGSGAVLGGGAVGGSANG--- 209

Mouse    61 LYQSPFASGYGLG---------------ADAYNLP--CAS---------------------YDQN 87
             |...:..|||..               :...:||  |:|                     .::.
  Fly   210 -YYGGYGGGYGTANGSVGSTHSQGHSPHSQMMDLPLQCSSTEPPTNTALGLQELGLKLEKRIEEA 273

Mouse    88 IP--------GL---CSDLAK--------------------GACDK--------ADEGVLHGPAE 113
            :|        |:   |.|:..                    |:.|.        :||.::....:
  Fly   274 VPAGQQLQELGMRLRCDDMGSENDDMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTD 338

Mouse   114 ASFRIYPWMR------------SSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHAL 166
            ....|||||:            ..|.:.||.|..|||:|.||||||||:||||||||||||||.|
  Fly   339 GERIIYPWMKKIHVAGVANGSYQPGMEPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTL 403

Mouse   167 CLTERQIKIWFQNRRMKWKKEHK------------DESQAPTAAPEDAVPSVSTAADKADEEEEE 219
            .|:|||||||||||||||||::|            |.:..||  |....|:...|:.|..:.:::
  Fly   404 VLSERQIKIWFQNRRMKWKKDNKLPNTKNVRKKTVDANGNPT--PVAKKPTKRAASKKQQQAQQQ 466

Mouse   220 EEEEEEEEEE 229
            ::.::::.::
  Fly   467 QQSQQQQTQQ 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hoxa7	NP_034585.1	Antp-type hexapeptide	118..123		4/4 (100%)
		Homeobox	133..185	CDD:278475	43/51 (84%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	186..229		9/54 (17%)
Dfd	NP_477201.1	Homeobox	370..422	CDD:278475	43/51 (84%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810