Protein Alignment Hoxa5 and HGTX

DIOPT Version :10

• Sequence 1: NP_034583.1
• Gene: Hoxa5 / 15402
• MGIID: 96177
• Length: 270
• Species: Mus musculus
• Sequence 2: NP_001368954.1
• Gene: HGTX / 53446
• FlyBaseID: FBgn0040318
• Length: 587
• Species: Drosophila melanogaster
• Alignment Length: 333
• Identity: 73/333 - (21%)
• Similarity: 106/333 - (31%)
• Gaps: 145/333 - (43%)

Mouse    68 ERARSYAAGASAAPAEPRYSQPATSTHSPPPDPLPCSAVAPSPGSD-----SHHGGKNSL----- 122
            :.|:|||....::.||    .|..::.|..|.|...:..:|...|.     .||.|.|.|
  Fly   209 DSAKSYALSQRSSGAE----DPCQTSESASPPPQGQNDYSPENLSSQRAKFQHHHGVNPLALHNA 269

Mouse   123 ---GN---------------------------------------SSGASAN------AGSTHISS 139
               ||                                       .|.||||      :.::|:.|
  Fly   270 NHAGNPGCHNNNNHMDHKLPLSFLGPPLAALHSMTTEMKGQGVGGSSASANGLSYSHSPNSHLIS 334

Mouse   140 REGVGTASAAEEDAPASSEQAGAQ---------SEPSPAPPA----------------------- 172
            ..|.|.:|::......::...||.         |:|.|...|
  Fly   335 DRGSGGSSSSSSTTTTNTNSQGAPNPHGIDTILSKPPPVTSAGLSALTGAGIPRFSIAAAAAGMA 399

Mouse   173 ----QPQIYP----------------------------WMRKL--------------HISHDNIG 191
                |.|..|                            |..:|              |.|:|..|
  Fly   400 QYLSQSQGAPLKTHAGHIVDRTHLYWPGLQGLVANPIAWRERLSNTMSANLSQSHQHHPSNDKDG 464

Mouse   192 GPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKL 256
              :.|..|..::..|...|||.|...:||....|.::|:||.:||.|:|:||||||.||:|.:
  Fly   465 --KKKHTRPTFSGQQIFALEKTFEQTKYLAGPERAKLAYALGMSESQVKVWFQNRRTKWRKRH-- 525

Mouse   257 KSMSMAAA 264
             :..||.|
  Fly   526 -AAEMATA 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hoxa5	NP_034583.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..175		32/193 (17%)
		Antp-type hexapeptide	176..181		2/32 (6%)
		Homeodomain	196..252	CDD:459649	25/55 (45%)
HGTX	NP_001368954.1	ROM1	179..>388	CDD:227709	35/182 (19%)
		Homeodomain	465..523	CDD:459649	25/57 (44%)