Protein Alignment Hoxa2 and Ptx1

DIOPT Version :10

• Sequence 1: NP_034581.1
• Gene: Hoxa2 / 15399
• MGIID: 96174
• Length: 372
• Species: Mus musculus
• Sequence 2: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Alignment Length: 410
• Identity: 88/410 - (21%)
• Similarity: 133/410 - (32%)
• Gaps: 138/410 - (33%)

Mouse    10 GFINSQPSLAECLTSFPPVADTFQSSSIKTSTLSH------------STLIPPPFEQTIPSLNPG 62
            |...|..:.:..|:|....:.|.......||...|            |..|.|.....:| ::..
  Fly    76 GSAESATTTSTALSSGSTGSSTVNGGGSSTSGTEHLHSHHSLHDSSSSVSISPAISSLMP-ISSL 139

Mouse    63 SHPRHGAG---VGGRPKSSPAGSRGSPVPAGALQPPEYP----------W--------------- 99
            ||..|.||   |||.          |..|...:.||..|          |
  Fly   140 SHLHHSAGQDLVGGY----------SQHPHHTVVPPHTPKHEPLEKLRIWAETGDFRDSHSSMTA 194

Mouse   100 ------------------------MKEKKAAKKTALPPAAASTGPACLGHKESLEIA------DG 134
                                    .:::|...::.......:...:..||.|.:..:      |.
  Fly   195 VANSLDSTHLNNFQTSSTSSISNRSRDRKDGNRSVNETTIKTENISSSGHDEPMTTSGEEPKNDK 259

Mouse   135 SGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMK-HKRQT 198
            .....||.||.:|:.||.|||..|..|:|.....|.|||...:|||.:|:|||:|||.| .||:.
  Fly   260 KNKRQRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEARVRVWFKNRRAKWRKRER 324

Mouse   199 QCKENQNSEGKFKNLEDSDKVEEDEEEKSLFEQALSVSGALLEREGYTFQQNALSQQQAPNGHNG 263
            .......:...||:...:..::...:: ||:.               ::..|..::..:|.|
  Fly   325 NAMNAAVAAADFKSGFGTQFMQPFADD-SLYS---------------SYPYNNWTKVPSPLG--- 370

Mouse   264 DSQTF--PVSPLTSNEKNLKHFQHQSPTVPNCLSTMGQNCGAGLNNDSPEAIEVPSLQDFNVFST 326
             ::.|  ||:||.|.... .|  ||:..  ||.:|........:||.|
  Fly   371 -TKPFPWPVNPLGSMVAG-NH--HQNSV--NCFNTGASGVAVSMNNAS----------------- 412

Mouse   327 DSCLQLSDALSPSLPGSLDS 346
                        .||||:.|
  Fly   413 ------------MLPGSMGS 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hoxa2	NP_034581.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	48..95		13/49 (27%)
		Antp-type hexapeptide	96..101		2/53 (4%)
		Homeodomain	140..196	CDD:459649	28/56 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..225		4/30 (13%)
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	28/55 (51%)