Protein Alignment Hoxa2 and C15

DIOPT Version :10

• Sequence 1: NP_034581.1
• Gene: Hoxa2 / 15399
• MGIID: 96174
• Length: 372
• Species: Mus musculus
• Sequence 2: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Alignment Length: 322
• Identity: 82/322 - (25%)
• Similarity: 116/322 - (36%)
• Gaps: 112/322 - (34%)

Mouse    14 SQPSLAECLTSFPPVADTFQSSSIKTSTLSHSTLIPPPFEQT---------IPSLNPGSHP-RHG 68
            |:..|:|.|.|     :..:|||.:....|.|.|:..|||.:         :.|.:|||.. .:.
  Fly    53 SETPLSESLQS-----EQTRSSSSENLPFSISRLLSKPFETSHHHHNNNNHLLSSSPGSSSNNNN 112

Mouse    69 AGVGGRPK-------------------SSPAGSRGS--------PVPAGA----LQPPEYP--WM 100
            :|..|..|                   :|..||..:        |..||.    :.|...|  |
  Fly   113 SGEKGEEKELLQQEDHDLAYKLATSIANSTYGSAAALYSYPHLYPSAAGGHVLRVPPQRTPLTW- 176

Mouse   101 KEKKAAKKTALPPAAASTGPACLGHKESLEIADGSGGGSRRL---------------RTAYTNTQ 150
                     ||||    ...|.|.|:...:....:...:||:               ||::|..|
  Fly   177 ---------ALPP----LHHAALAHQAVKDRLAAAFPIARRIGHPYQNRTPPKRKKPRTSFTRIQ 228

Mouse   151 LLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKFKNLED 215
            :.||||.||..|||....|..:|..|.:|:.|||.||||||.|.:|||
  Fly   229 VAELEKRFHKQKYLASAERAALARGLKMTDAQVKTWFQNRRTKWRRQT----------------- 276

Mouse   216 SDKVEEDEEEKSLFEQALSVSGALLEREGYTFQQNALSQ----QQAPNGHNGDSQTFPVSPL 273
               .||.|.|:....:.:           .:.|..|:|:    ..||.|..|.....|::.|
  Fly   277 ---AEEREAERQAANRLM-----------LSLQAEAISKGFAPPSAPLGSQGGVNGAPLAAL 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hoxa2	NP_034581.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	48..95		16/87 (18%)
		Antp-type hexapeptide	96..101		2/6 (33%)
		Homeodomain	140..196	CDD:459649	29/70 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..225		6/30 (20%)
C15	NP_476873.2	COG5576	<196..315	CDD:227863	42/149 (28%)
		Homeodomain	218..274	CDD:459649	27/55 (49%)