Protein Alignment Hoxa2 and Scr

DIOPT Version :10

• Sequence 1: NP_034581.1
• Gene: Hoxa2 / 15399
• MGIID: 96174
• Length: 372
• Species: Mus musculus
• Sequence 2: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Alignment Length: 358
• Identity: 95/358 - (26%)
• Similarity: 128/358 - (35%)
• Gaps: 146/358 - (40%)

Mouse    42 LSHSTLIPPPFEQTIPSLNPG---------------SHPRHGAGVGGRPKS------SPAG---- 81
            ||.|:::    |....|||.|               ::...|:||.|.|.:      ||.|
  Fly   219 LSPSSVV----ESVARSLNKGVLGGSLAAAAAAAGLNNNHSGSGVSGGPGNVNVPMHSPGGGDSD 279

Mouse    82 -SRGSPVPAGALQ--------PPE-YPWMKEKKAAKKTALPPAAASTGPACLGHKESLEIADGSG 136
             ...|...||:.|        ||: |||||.......|.                       .:.
  Fly   280 SESDSGNEAGSSQNSGNGKKNPPQIYPWMKRVHLGTSTV-----------------------NAN 321

Mouse   137 GGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCK 201
            |.::|.||:||..|.||||||||||:||.|.||:|||..|.|||||:|:||||||||.|     |
  Fly   322 GETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWK-----K 381

Mouse   202 ENQNSE----------------------GKFKNLEDSDKVE---EDEEEKSLFEQALSVSGALLE 241
            |::.:.                      .:|.:|...|...   .......|:::....:.|...
  Fly   382 EHKMASMNIVPYHMGPYGHPYHQFDIHPSQFAHLSAXDAWHFSGTGXRLNQLYQEPYQTAAAASA 446

Mouse   242 REGYTFQQNALSQQQAP---------NGHNGDSQTFPVSPLTSNEKNLKHFQHQSPTVPNCLSTM 297
            ..||.      ||...|         .|..|                           |..|:..
  Fly   447 ASGYQ------SQDGGPIGGGSVGVGGGAGG---------------------------PGSLANG 478

Mouse   298 GQNCGAGLN---------NDSPEAIEVPSLQDF 321
            |.| |:|.|         :.:|:.|:.|  |:|
  Fly   479 GSN-GSGPNSLFASAASSSQAPDCIKYP--QEF 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hoxa2	NP_034581.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	48..95		17/80 (21%)
		Antp-type hexapeptide	96..101		3/5 (60%)
		Homeodomain	140..196	CDD:459649	39/55 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..225		6/55 (11%)
Scr	NP_001368995.1	Homeodomain	325..381	CDD:459649	40/60 (67%)