Protein Alignment Hoxa2 and en

DIOPT Version :10

• Sequence 1: NP_034581.1
• Gene: Hoxa2 / 15399
• MGIID: 96174
• Length: 372
• Species: Mus musculus
• Sequence 2: NP_523700.2
• Gene: en / 36240
• FlyBaseID: FBgn0000577
• Length: 552
• Species: Drosophila melanogaster
• Alignment Length: 259
• Identity: 76/259 - (29%)
• Similarity: 105/259 - (40%)
• Gaps: 74/259 - (28%)

Mouse    14 SQPSL---AECLTSFPPV--ADTFQS-SSIKTSTLSHSTLIPPPFEQTIPSLNPGSHPRHGAGVG 72
            :||.|   |..|.|.||.  |.|..| ||:.||:.|.|:    .......|||  |.|
  Fly   315 TQPPLSSSASSLASPPPASNASTISSTSSVATSSSSSSS----GCSSAASSLN--SSP------- 366

Mouse    73 GRPKSSPAGSRGSPVPAGALQPPEYPWMKEKKAAKKTALPPAAAS--------------TGPACL 123
                ||..|:.||.|.|.:.||...|             ||:|.|              ||....
  Fly   367 ----SSRLGASGSGVNASSPQPQPIP-------------PPSAVSRDSGMESSDDTRSETGSTTT 414

Mouse   124 -GHKESL--------EIADGSGGGSR---------------RLRTAYTNTQLLELEKEFHFNKYL 164
             |.|..:        ..:|....|.|               |.|||:::.||..|::||:.|:||
  Fly   415 EGGKNEMWPAWVYCTRYSDRPSSGPRYRRPKQPKDKTNDEKRPRTAFSSEQLARLKREFNENRYL 479

Mouse   165 CRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKFKNLEDSDKVEEDEEEKSL 228
            ...||.::::.|.|.|.|:|:||||:|.|.|:.|..|.....:...:.|.:...|...:||:.|
  Fly   480 TERRRQQLSSELGLNEAQIKIWFQNKRAKIKKSTGSKNPLALQLMAQGLYNHTTVPLTKEEEEL 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hoxa2	NP_034581.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	48..95		13/46 (28%)
		Antp-type hexapeptide	96..101		1/4 (25%)
		Homeodomain	140..196	CDD:459649	26/70 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..225		5/30 (17%)
en	NP_523700.2	Homeodomain	455..511	CDD:459649	25/55 (45%)
		Engrail_1_C_sig	512..542	CDD:431338	6/29 (21%)