Protein Alignment RNF145 and Rnf145

DIOPT Version :9

• Sequence 1: NP_001186309.1
• Gene: RNF145 / 153830
• HGNCID: 20853
• Length: 693
• Species: Homo sapiens
• Sequence 2: NP_001099248.1
• Gene: Rnf145 / 287212
• RGDID: 1309561
• Length: 664
• Species: Rattus norvegicus
• Alignment Length: 664
• Identity: 627/664 - (94%)
• Similarity: 636/664 - (95%)
• Gaps: 1/664 - (0%)

Human    31 MAAKEKLEAVLNVALRVPSIMLLDVLYRWDVSSFFQQIQRSSLSNNPLFQYKYLALNMHYVGYIL 95
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat     1 MAAKEKLEAVLNVALRVPSIMLLDVLYRWDVSSFFQQIQRSSLSNNPLFQYKYLALNMHYVGYIL 65

Human    96 SVVLLTLPRQHLVQLYLYFLTALLLYAGHQISRDYVRSELEFAYEGPMYLEPLSMNRFTTALIGQ 160
            |||||||||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||
  Rat    66 SVVLLTLPRQHLVQLYLYFLTALLLYAGHQISRDYVRSELESAYEGPMYLEPLSMNRFTTALIGQ 130

Human   161 LVVCTLCSCVMKTKQIWLFSAHMLPLLARLCLVPLETIVIINKFAMIFTGLEVLYFLGSNLLVPY 225
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   131 LVVCTLCSCVMKTKQIWLFSAHMLPLLARLCLVPLETIVIINKFAMIFTGLEVLYFLGSNLLVPY 195

Human   226 NLAKSAYRELVQVVEVYGLLALGMSLWNQLVVPVLFMVFWLVLFALQIYSYFSTRDQPASRERLL 290
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   196 NLAKSAYRELVQVVEVYGLLALGMSLWNQLVVPVLFMVFWLVLFALQIYSYFSTRDQPASRERLL 260

Human   291 FLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILA 355
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   261 FLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILA 325

Human   356 VQTGLIELQVVHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLL 420
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   326 VQTGLIELQVVHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLL 390

Human   421 VFPAYMAYMICQFFHMDFWLLIIISSSILTSLQVLGTLFIYVLFMVEEFRKEPVENMDDVIYYVN 485
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   391 VFPAYMAYMICQFFHMDFWLLIIISSSILTSLQVLGTLFIYVLFMVEEFRKEPVENMDDVIYYVN 455

Human   486 GTYRLLEFLVALCVVAYGVSETIFGEWTVMGSMIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIK 550
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   456 GTYRLLEFLVALCVVAYGVSETIFGEWTVMGSMIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIK 520

Human   551 SLPIATKEQLEKHNDICAICYQDMKSAVITPCSHFFHAGCLKKWLYVQETCPLCHCHLKNSSQLP 615
            |||||||||||:||||||||||||||||||||||||||||||||||||:||||||||||||||||
  Rat   521 SLPIATKEQLERHNDICAICYQDMKSAVITPCSHFFHAGCLKKWLYVQDTCPLCHCHLKNSSQLP 585

Human   616 GLGTEPVLQPH-AGAEQNVMFQEGTEPPGQEHTPGTRIQEGSRDNNEYIARRPDNQEGAFDPKEY 679
            ||||||..||. ||||||::.|||.|||..|..||...||||.||:|||.|...::||..||.:.
  Rat   586 GLGTEPAPQPPVAGAEQNIVLQEGPEPPDHETPPGPGAQEGSGDNSEYINRSSASREGDADPGDG 650

Human   680 PHSAKDEAHPVESA 693
            |..|:.||.||.||
  Rat   651 PQIAEGEACPVASA 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RNF145	NP_001186309.1	TRC8_N	38..536	CDD:290425	496/497 (100%)
		zf-rbx1	<564..605	CDD:289448	39/40 (98%)
		zf-RING_2	565..605	CDD:290367	38/39 (97%)
Rnf145	NP_001099248.1	TRC8_N	8..506	CDD:404574	496/497 (100%)
		HRD1	<520..643	CDD:227568	97/122 (80%)
		RING-H2_RNF145	533..575	CDD:319598	40/41 (98%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83693431
Domainoid	1	1.000	979	1.000	Domainoid score	I1648
eggNOG	1	0.900	-	-		E1_COG5243
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H14427
Inparanoid	1	1.050	1238	1.000	Inparanoid score	I3863
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG46488
OrthoDB	1	1.010	-	-		D119734at7742
OrthoFinder	1	1.000	-	-		FOG0006288
OrthoInspector	1	1.000	-	-		oto143090
orthoMCL	1	0.900	-	-		OOG6_109881
Panther	1	1.100	-	-	LDO	PTHR22763
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4575
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	18.270