DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment BTNL9 and Btnl9

DIOPT Version :9

Sequence 1:XP_024310148.1 Gene:BTNL9 / 153579 HGNCID:24176 Length:564 Species:Homo sapiens
Sequence 2:XP_038943086.1 Gene:Btnl9 / 684480 RGDID:1590287 Length:529 Species:Rattus norvegicus


Alignment Length:570 Identity:375/570 - (65%)
Similarity:407/570 - (71%) Gaps:48/570 - (8%)


- Green bases have known domain annotations that are detailed below.


Human     1 MVDLSVSPDSLK--PVSLTSSLVFLMHLLLLQPGEPSS-EVKVLGPEYPILALVGEEVEFPCHLW 62
            |.|.||....||  |..||   :|..:||.||..|.:| ||.|||||..|||.|||.|||||.|.
  Rat     1 MADFSVLLGFLKQTPWCLT---IFFTYLLFLQLWEVNSDEVWVLGPEESILARVGEAVEFPCRLS 62

Human    63 PQLDAQQMEIRWFRSQTFNVVHLYQEQQELPGRQMPAFRNRTKLVKDDIAYGSVVLQLHSIIPSD 127
            ...||..|||.|||:|..|||:||||.|.....||..|||||.....||..|||.|.:.|::|||
  Rat    63 SYQDAGYMEILWFRTQVSNVVYLYQEPQGRSNPQMAQFRNRTLFEAYDIGEGSVNLHILSVVPSD 127

Human   128 KGTYGCRFHSDNFSGEALWELEVAGLGSDPHLSLEGFKEGGIQLRLRSSGWYPKPKVQWRDHQGQ 192
            :|.|||||.|.||||||.|||||||||||||:|||||...||||:..|||||||||||||.||.|
  Rat   128 EGRYGCRFLSHNFSGEATWELEVAGLGSDPHISLEGFNGEGIQLQCSSSGWYPKPKVQWRGHQDQ 192

Human   193 CLPPEFEAIVWDAQDLFSLETSVVVRAGALSNVSVSIQNLLLSQKKELVVQIADVFVPGASAWKS 257
            ||.||.|.|..:||.||||||||:||.|..||||..|||.||.||||.|:||||||:|..|.||.
  Rat   193 CLSPESEDITQNAQGLFSLETSVIVRGGTHSNVSCIIQNPLLPQKKEFVLQIADVFLPRTSPWKK 257

Human   258 AFVAT---LPLLLV-LAALALGVLRKQRRSREKLRKQAEKRQEKLTAELEKLQTELDWRRAEGQA 318
            |||.|   |||.|| ||.|||....||||.:|...||.|:       :.|||||||||||:||||
  Rat   258 AFVGTLVVLPLCLVALAVLALRYFYKQRRFQENRVKQGEQ-------DREKLQTELDWRRSEGQA 315

Human   319 EWRAAQKYAEKREVCPPWGRHGRGPDRPGRALTLWLCAVDVTLDPASAHPSLEVSEDGKSVSSRG 383
            ||||||:|                             |||||||||:||||||||.:.||||||.
  Rat   316 EWRAAQQY-----------------------------AVDVTLDPATAHPSLEVSNNRKSVSSRL 351

Human   384 APPGPAPGHPQRFSEQTCALSLERFSAGRHYWEVHVGRRSRWFLGACLAAVPRAGPARLSPAAGY 448
            ..|..|.|.|||||||||.||.||||:|||||||||||||||||||||.:|.|:|||||||||||
  Rat   352 GVPSTAAGDPQRFSEQTCVLSRERFSSGRHYWEVHVGRRSRWFLGACLESVERSGPARLSPAAGY 416

Human   449 WVLGLWNGCEYFVLAPHRVALTLRVPPRRLGVFLDYEAGELSFFNVSDGSHIFTFHDTFSGALCA 513
            ||:||||.||||||.||||||.|||||||:||.||||||:|||||||||||||:|.|||||.|||
  Rat   417 WVMGLWNRCEYFVLDPHRVALALRVPPRRVGVLLDYEAGKLSFFNVSDGSHIFSFTDTFSGTLCA 481

Human   514 YFRPRAHDGGEHPDPLTICPLPVRGTGVPEENDSDTWLQPYEPADPALDW 563
            |||||||||.|||||:|||.|||||..:.||||:|.|||||||.|||  |
  Rat   482 YFRPRAHDGSEHPDPMTICSLPVRGLQINEENDNDNWLQPYEPLDPA--W 529

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
BTNL9XP_024310148.1 Ig_MOG_like 52..151 CDD:319291 59/98 (60%)
bZIP <281..317 CDD:328730 18/35 (51%)
SPRY_PRY_C-I_1 358..532 CDD:293968 143/173 (83%)
Btnl9XP_038943086.1 Ig 40..151 CDD:416386 68/110 (62%)
FR1 40..61 CDD:409353 16/20 (80%)
Ig strand A 40..43 CDD:409353 2/2 (100%)
Ig strand A' 46..50 CDD:409353 2/3 (67%)
Ig strand B 53..61 CDD:409353 6/7 (86%)
CDR1 62..70 CDD:409353 2/7 (29%)
Ig strand C 70..75 CDD:409353 3/4 (75%)
FR2 71..75 CDD:409353 2/3 (67%)
CDR2 76..94 CDD:409353 10/17 (59%)
Ig strand C' 80..88 CDD:409353 5/7 (71%)
Ig strand C' 89..92 CDD:409353 1/2 (50%)
FR3 96..136 CDD:409353 22/39 (56%)
Ig strand D 103..108 CDD:409353 2/4 (50%)
Ig strand E 114..122 CDD:409353 4/7 (57%)
Ig strand F 129..137 CDD:409353 6/7 (86%)
CDR3 137..139 CDD:409353 1/1 (100%)
Ig strand G 139..151 CDD:409353 10/11 (91%)
FR4 140..151 CDD:409353 9/10 (90%)
Ig 157..234 CDD:416386 53/76 (70%)
SPRY_PRY_C-I_1 326..500 CDD:293968 143/173 (83%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C83684135
Domainoid 1 1.000 200 1.000 Domainoid score I24245
eggNOG 00.000 Not matched by this tool.
HGNC 1 1.500 - -
Hieranoid 1 1.000 - -
Homologene 1 1.000 - - H68540
Inparanoid 1 1.050 708 1.000 Inparanoid score I8697
NCBI 1 1.000 - -
OMA 1 1.010 - - QHG39342
OrthoDB 1 1.010 - - D175892at32523
OrthoFinder 1 1.000 - - FOG0001727
OrthoInspector 1 1.000 - - oto140090
orthoMCL 1 0.900 - - OOG6_131489
Panther 1 1.100 - - LDO PTHR24100
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
1515.410

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