DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BTNL9 and side-III

DIOPT Version :9

Sequence 1:	XP_024310148.1	Gene:	BTNL9 / 153579	HGNCID:	24176	Length:	564	Species:	Homo sapiens
Sequence 2:	NP_001036681.1	Gene:	side-III / 4379844	FlyBaseID:	FBgn0083949	Length:	1689	Species:	Drosophila melanogaster

Alignment Length:	228	Identity:	50/228 - (21%)
Similarity:	72/228 - (31%)	Gaps:	95/228 - (41%)

- Green bases have known domain annotations that are detailed below.

Human    14 VSLTSSLVFLMHLLLL-------QPGEPSSEVKVLGPEYPILALVGEEVEFPCHLWPQL-DAQQM 70
            ::|.:..:|..|:.|.       ...:|.|.|.|       .|::|.....||.:.|:. |.:..
  Fly    26 LALFALFLFAAHISLTSGQIDWDDDDDPVSTVAV-------EAVLGRTASLPCDIEPEAKDDRVY 83

Human    71 EIRWFRSQTFNVVHLYQEQQELPGR-----------------------QMPAFRNRTKLVKDDIA 112
            .:.|||......::.:    ::.||                       |.||     ||..|:|
  Fly    84 MVLWFRESAGKPLYSF----DVRGRPFEKALYWSDTNSFGPRAYFVTGQQPA-----KLSVDNI- 138

Human   113 YGSVVLQLHSIIPSDKGTYGCRFHSDN-----------------------FSGEALWELEVAG-L 153
                  ||     .|:|.|.||....|                       .||.     :||| :
  Fly   139 ------QL-----DDEGVYRCRVDFQNSPTRNHRINLTVIVPPHQILVYDASGR-----DVAGAV 187

Human   154 GSDPHLSLEGFKEGGIQLRLRSSGWYPKPKVQW 186
            |.    .|||   ..|.|.....|..|:|.|.|
  Fly   188 GP----LLEG---DNIVLTCEVRGGRPEPTVTW 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BTNL9	XP_024310148.1	Ig_MOG_like	52..151	CDD:319291	27/145 (19%)
		bZIP	<281..317	CDD:328730
		SPRY_PRY_C-I_1	358..532	CDD:293968
side-III	NP_001036681.1	IG_like	59..166	CDD:214653	27/134 (20%)
		V-set	59..166	CDD:284989	27/134 (20%)
		ig	190..268	CDD:278476	10/27 (37%)
		IG_like	192..259	CDD:214653	9/25 (36%)
		Ig	296..361	CDD:299845
		IG_like	391..468	CDD:214653
		IGc2	392..454	CDD:197706
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910