DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mnx1 and ftz

DIOPT Version :9

Sequence 1:	NP_064328.2	Gene:	Mnx1 / 15285	MGIID:	109160	Length:	404	Species:	Mus musculus
Sequence 2:	NP_477498.1	Gene:	ftz / 40834	FlyBaseID:	FBgn0001077	Length:	410	Species:	Drosophila melanogaster

Alignment Length:	163	Identity:	52/163 - (31%)
Similarity:	76/163 - (46%)	Gaps:	16/163 - (9%)

- Green bases have known domain annotations that are detailed below.

Mouse   180 PALSYSYPQVQGAHPAHPADPIKLGASTFQLDQWLRASTAGMILPK-MPDFS-SQAQSNLLGKC- 241
            |....|.|.::|. ...|..|.:..:|....:...|..||    |. ..||: |..:..|...|
  Fly   193 PTTPTSLPPLEGI-STPPQSPGEKSSSAVSQEINHRIVTA----PNGAGDFNWSHIEETLASDCK 252

Mouse   242 --RRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKKAKE 304
              :|.|..:|..|.||||.:|..|:|::|.:|.::|.:|.|:|.|:|||||||||      |:|:
  Fly   253 DSKRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKIWFQNRRM------KSKK 311

Mouse   305 QAAQEAEKQKGGGGGTGKGGSEEKTEEELMGPP 337
            ....::..:..|.|.|......|.|.....|.|
  Fly   312 DRTLDSSPEHCGAGYTAMLPPLEATSTATTGAP 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mnx1	NP_064328.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	36..80
		Homeobox	244..297	CDD:278475	26/52 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	299..404		9/39 (23%)
ftz	NP_477498.1	FTZ	1..248	CDD:281812	14/59 (24%)
ftz	NP_477498.1	Homeobox	257..310	CDD:278475	27/58 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.900