| Sequence 1: | NP_001288233.1 | Gene: | Hipk1 / 15257 | MGIID: | 1314873 | Length: | 1210 | Species: | Mus musculus |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001286884.1 | Gene: | CG7028 / 38032 | FlyBaseID: | FBgn0027587 | Length: | 912 | Species: | Drosophila melanogaster |
| Alignment Length: | 498 | Identity: | 142/498 - (28%) |
|---|---|---|---|
| Similarity: | 226/498 - (45%) | Gaps: | 86/498 - (17%) |
- Green bases have known domain annotations that are detailed below.
|
Mouse 54 GQAS-SSHQVANFNLPAYDQG--------------LLLPAPAVEHIVVTAADSSGSAATATFQSS 103
Mouse 104 QTLTHRSNVSLLEPYQKCGLKRK--------SEEVESNGSVQIIEEHPPLMLQNRTVVGAAATTT 160
Mouse 161 TVTTKSSSSSGEGDYQLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKRSTKEI-VAIKILKNH 224
Mouse 225 PSYARQGQIEVSILSRLS-SENADEYNFVRSYECFQHKNHTCLVFEMLEQNLYDFLKQ-NKFSPL 287
Mouse 288 PLKYIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKAVCSTY 352
Mouse 353 LQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLS 417
Mouse 418 AGTKTTRFFNRDPNLGYPLWRLKTPEEHELETGIKSKEARKYIFNCLDDMAQVNMSTDLEGTDML 482
Mouse 483 AEK---ADRREYI----DLLKKMLTIDADKRITPLKTLNHQFV 518 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Hipk1 | NP_001288233.1 | STKc_HIPK1 | 174..528 | CDD:271130 | 116/355 (33%) |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 835..856 | ||||
| Nuclear localization signal 1 (NLS1). /evidence=ECO:0000250 | 844..847 | ||||
| Interaction with TP53. /evidence=ECO:0000269|PubMed:12702766 | 885..1093 | ||||
| Required for localization to nuclear speckles. /evidence=ECO:0000250 | 891..998 | ||||
| SUMO interaction motifs (SIM), required for nuclear localization and kinase activity. /evidence=ECO:0000250 | 902..926 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 938..981 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1046..1069 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1084..1104 | ||||
| CG7028 | NP_001286884.1 | STKc_PRP4 | 591..908 | CDD:271037 | 111/338 (33%) |
| S_TKc | 599..908 | CDD:214567 | 109/330 (33%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG0667 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.810 | |||||