DRSC/TRiP Functional Genomics Resources

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Protein Alignment CXADR and Cxadr

DIOPT Version :9

Sequence 1:NP_001329.1 Gene:CXADR / 1525 HGNCID:2559 Length:365 Species:Homo sapiens
Sequence 2:XP_006248062.1 Gene:Cxadr / 89843 RGDID:619794 Length:365 Species:Rattus norvegicus


Alignment Length:365 Identity:332/365 - (90%)
Similarity:347/365 - (95%) Gaps:0/365 - (0%)


- Green bases have known domain annotations that are detailed below.


Human     1 MALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQ 65
            |||||||||||||.||..||||||||:.|||||||||||||||||.|||||||||||||||:|||
  Rat     1 MALLLCFVLLCGVADFTSSLSITTPEQRIEKAKGETAYLPCKFTLEPEDQGPLDIEWLISPSDNQ 65

Human    66 KVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVAN 130
            ||||||||||||||||:|||||||||||||||:||||||||||||||||||||||||||||||||
  Rat    66 KVDQVIILYSGDKIYDNYYPDLKGRVHFTSNDVKSGDASINVTNLQLSDIGTYQCKVKKAPGVAN 130

Human   131 KKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSS 195
            :|..|.|||||||.||:||||.|||:|||:||||||||||||||||||||||||||.|||||||.
  Rat   131 RKFLLTVLVKPSGTRCFVDGSGEIGNDFKLKCEPKEGSLPLQYEWQKLSDSQKMPTPWLAEMTSP 195

Human   196 VISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGLIAGAIIGTLLALALIGLIIFCC 260
            |||||||||||||||||||:||||||||:|||:||||||:||.||||:|||||||.|||.|:|||
  Rat   196 VISVKNASSEYSGTYSCTVQNRVGSDQCMLRLDVVPPSNRAGTIAGAVIGTLLALVLIGAILFCC 260

Human   261 RKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHSSLGSMSPSNMEGYSKTQYNQVPSED 325
            .||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   261 HKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHSSLGSMSPSNMEGYSKTQYNQVPSED 325

Human   326 FERTPQSPTLPPAKVAAPNLSRMGAIPVMIPAQSKDGSIV 365
            |||.||||||.||||||||||||||:||||||||||||||
  Rat   326 FERAPQSPTLAPAKVAAPNLSRMGAVPVMIPAQSKDGSIV 365

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CXADRNP_001329.1 IgV_CAR_like 20..136 CDD:409552 106/115 (92%)
Ig strand B 37..41 CDD:409552 3/3 (100%)
Ig strand C 54..58 CDD:409552 3/3 (100%)
Ig strand E 103..107 CDD:409552 3/3 (100%)
Ig strand F 117..122 CDD:409552 4/4 (100%)
Ig strand G 130..133 CDD:409552 1/2 (50%)
IG 155..229 CDD:214652 67/73 (92%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 269..343 71/73 (97%)
PDZ-binding 360..365 4/4 (100%)
CxadrXP_006248062.1 V-set 24..138 CDD:284989 103/113 (91%)
IG_like 27..137 CDD:214653 100/109 (92%)
IG_like 149..229 CDD:214653 72/79 (91%)
Ig 154..222 CDD:299845 62/67 (93%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 270 1.000 Domainoid score I17466
eggNOG 1 0.900 - - E1_28JJZ
HGNC 1 1.500 - -
Hieranoid 1 1.000 - -
Homologene 1 1.000 - - H1024
Inparanoid 1 1.050 681 1.000 Inparanoid score I9052
NCBI 1 1.000 - -
OMA 1 1.010 - - QHG39098
OrthoDB 1 1.010 - - D134281at9347
OrthoFinder 1 1.000 - - FOG0001092
OrthoInspector 1 1.000 - - oto136881
orthoMCL 1 0.900 - - OOG6_118669
Panther 1 1.100 - - LDO PTHR44468
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X10006
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
1717.340

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