DRSC/TRiP Functional Genomics Resources

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Protein Alignment CXADR and DIP-epsilon

DIOPT Version :9

Sequence 1:NP_001329.1 Gene:CXADR / 1525 HGNCID:2559 Length:365 Species:Homo sapiens
Sequence 2:NP_001137799.1 Gene:DIP-epsilon / 7354433 FlyBaseID:FBgn0259714 Length:467 Species:Drosophila melanogaster


Alignment Length:345 Identity:67/345 - (19%)
Similarity:117/345 - (33%) Gaps:114/345 - (33%)


- Green bases have known domain annotations that are detailed below.


Human    24 TPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLK 88
            |..::|.: :|:...|.||...|||.    .|:|.....:...:::.:                 
  Fly   164 TSSDIIVR-EGDNVTLRCKAKGSPEP----TIKWKRDDGNKIVINKTL----------------- 206

Human    89 GRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKK-APGVANKKIHLVVLVKPSGARCYVDGSE 152
             .||....|      |:.:..:....:|.|.|.... .|...:|:|.:.|...|.....:.....
  Fly   207 -EVHDLETD------SLELERISRLHMGAYLCIASNGVPPSVSKRIKVSVDFSPMVWIPHQLVGI 264

Human   153 EIGSDFKIKCEPKEGSLPLQYEW-----QKLSDSQKMPT-------SWLAEMTSSVISVKNASSE 205
            .||.:..::|..:.....|.| |     |.:::|.|..|       |:.|.|..::.:|:  ||:
  Fly   265 PIGFNITLECFIEANPTSLNY-WTRENDQMITESSKYKTETIPGHPSYKATMRLTITNVQ--SSD 326

Human   206 YSGTYSCTVRNRVGSDQCLLRLNV-VPPSNKAGLIAGAIIGTLLALALIGLIIFCCRKKRREEKY 269
            | |.|.|..:|..|.....::|.: .||:.:                                  
  Fly   327 Y-GNYKCVAKNPRGDMDGNIKLYMSSPPTTQ---------------------------------- 356

Human   270 EKEVHHDIREDVPPPKS----RTSTARS------YIGS--NHSSLGSM--SPSN---MEGYSKTQ 317
                        |||.:    ||:|..:      ||.:  |.:.:|.:  .|:|   ..|.|..:
  Fly   357 ------------PPPTTTTLRRTTTTAAEIALDGYINTPLNGNGIGIVGEGPTNSVIASGKSSIK 409

Human   318 Y----NQVPSEDFERTPQSP 333
            |    |::.....:.|..||
  Fly   410 YLSNLNEIDKSKQKLTGSSP 429

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CXADRNP_001329.1 IgV_CAR_like 20..136 CDD:409552 21/112 (19%)
Ig strand B 37..41 CDD:409552 1/3 (33%)
Ig strand C 54..58 CDD:409552 1/3 (33%)
Ig strand E 103..107 CDD:409552 1/3 (33%)
Ig strand F 117..122 CDD:409552 2/4 (50%)
Ig strand G 130..133 CDD:409552 1/2 (50%)
IG 155..229 CDD:214652 22/85 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 269..343 19/86 (22%)
PDZ-binding 360..365
DIP-epsilonNP_001137799.1 IG_like 59..155 CDD:214653
Ig 69..139 CDD:143165
IG_like 165..249 CDD:214653 20/112 (18%)
IGc2 172..237 CDD:197706 16/92 (17%)
IG_like 267..348 CDD:214653 21/84 (25%)
Ig 270..339 CDD:299845 19/72 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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