DRSC/TRiP Functional Genomics Resources

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Protein Alignment CXADR and Cxadr

DIOPT Version :9

Sequence 1:NP_001329.1 Gene:CXADR / 1525 HGNCID:2559 Length:365 Species:Homo sapiens
Sequence 2:NP_001020363.1 Gene:Cxadr / 13052 MGIID:1201679 Length:365 Species:Mus musculus


Alignment Length:365 Identity:328/365 - (89%)
Similarity:345/365 - (94%) Gaps:0/365 - (0%)


- Green bases have known domain annotations that are detailed below.


Human     1 MALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQ 65
            ||.|||||||||:.||...|||||||:.|||||||||||||||||||||||||||||||||:|||
Mouse     1 MARLLCFVLLCGIADFTSGLSITTPEQRIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPSDNQ 65

Human    66 KVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVAN 130
            .|||||||||||||||:|||||||||||||||:||||||||||||||||||||||||||||||||
Mouse    66 IVDQVIILYSGDKIYDNYYPDLKGRVHFTSNDVKSGDASINVTNLQLSDIGTYQCKVKKAPGVAN 130

Human   131 KKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSS 195
            ||..|.|||||||.||:||||||||:|||:||||||||||||:|||||||||.|||.|||||||.
Mouse   131 KKFLLTVLVKPSGTRCFVDGSEEIGNDFKLKCEPKEGSLPLQFEWQKLSDSQTMPTPWLAEMTSP 195

Human   196 VISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGLIAGAIIGTLLALALIGLIIFCC 260
            |||||||||||||||||||:||||||||:|||:||||||:||.||||:|||||||.|||.|:|||
Mouse   196 VISVKNASSEYSGTYSCTVQNRVGSDQCMLRLDVVPPSNRAGTIAGAVIGTLLALVLIGAILFCC 260

Human   261 RKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHSSLGSMSPSNMEGYSKTQYNQVPSED 325
            .:|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   261 HRKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHSSLGSMSPSNMEGYSKTQYNQVPSED 325

Human   326 FERTPQSPTLPPAKVAAPNLSRMGAIPVMIPAQSKDGSIV 365
            |||.||||||.||||||||||||||:||||||||||||||
Mouse   326 FERAPQSPTLAPAKVAAPNLSRMGAVPVMIPAQSKDGSIV 365

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CXADRNP_001329.1 IgV_CAR_like 20..136 CDD:409552 107/115 (93%)
Ig strand B 37..41 CDD:409552 3/3 (100%)
Ig strand C 54..58 CDD:409552 3/3 (100%)
Ig strand E 103..107 CDD:409552 3/3 (100%)
Ig strand F 117..122 CDD:409552 4/4 (100%)
Ig strand G 130..133 CDD:409552 2/2 (100%)
IG 155..229 CDD:214652 65/73 (89%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 269..343 71/73 (97%)
PDZ-binding 360..365 4/4 (100%)
CxadrNP_001020363.1 V-set 24..138 CDD:369466 104/113 (92%)
ig 154..222 CDD:365836 60/67 (90%)
TM_EGFR-like 238..271 CDD:213052 25/32 (78%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 269..315 45/45 (100%)
PDZ-binding. /evidence=ECO:0000250 360..365 4/4 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 269 1.000 Domainoid score I18356
eggNOG 1 0.900 - - E1_28JJZ
HGNC 1 1.500 - -
Hieranoid 1 1.000 - -
Homologene 1 1.000 - - H1024
Inparanoid 1 1.050 674 1.000 Inparanoid score I9582
Isobase 00.000 Not matched by this tool.
NCBI 1 1.000 - -
OMA 1 1.010 - - QHG39098
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0001092
OrthoInspector 1 1.000 - - oto120615
orthoMCL 1 0.900 - - OOG6_118669
Panther 1 1.100 - - LDO PTHR44468
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R6005
SonicParanoid 1 1.000 - - X10006
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
1616.360

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