Protein Alignment IGSF11 and side

DIOPT Version :9

• Sequence 1: NP_001340247.1
• Gene: IGSF11 / 152404
• HGNCID: 16669
• Length: 481
• Species: Homo sapiens
• Sequence 2: NP_001247334.1
• Gene: side / 43300
• FlyBaseID: FBgn0016061
• Length: 986
• Species: Drosophila melanogaster
• Alignment Length: 607
• Identity: 122/607 - (20%)
• Similarity: 189/607 - (31%)
• Gaps: 234/607 - (38%)

Human    22 RGQHTSGPAGGRGV------------IQDMYSQLAVGKKTERDRHVGRSLYWGPSCYPSVAASLE 74
            |...|..|..|:.:            :|.:.|..|..:..:..:::...|.|
  Fly    50 RKSRTRCPDNGKTIWAVGFTLVLLTCLQQLKSVSADEESQDFQKNIPARLVW------------- 101

Human    75 VSESPGSIQVARGQPAVLPCTFT--TSAALINLNVIWMV----TPLSNANQ--------PEQVIL 125
                     .|.|:...|||..|  ||...:.| ::|..    .||.:.:.        |...|.
  Fly   102 ---------AALGKTVELPCDLTPPTSQDSVKL-LLWFKDTTGIPLYSLDSRGGNVKLAPHAAIA 156

Human   126 YQGGQMFDGAPRFHGRVGFT-GTMPATNVSIFINNTQLSDTGTYQCLVN--NLPDIGGRNIGVTG 187
            ...||          |:.|: |..|..: .:.||:.:..|.|.|:|.|:  |.|....|:    .
  Fly   157 SDLGQ----------RLFFSIGDNPKDS-RLQINDVKPEDGGVYRCRVDFFNSPTRNFRH----N 206

Human   188 LTVLVPPSAPH---------CQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTL-------- 235
            ||::|||..|.         .|:.|....|.::.|.|....|.|.|...|.:.|..|
  Fly   207 LTLVVPPEEPRIFDAQGKEISQMAGPFREGYELFLCCQVRGGRPPPKVTWWRDDTELIGTSHTSV 271

Human   236 ----------KLPPTATQD--------QVQGT---------VTIR-------------------- 253
                      .|..|.|:|        :.|||         ||::
  Fly   272 EEGATVMVNQLLIGTTTRDFYGIRIECRAQGTRLVDPVRKDVTVQVYLKPVRVKIATPNELLTAG 336

Human   254 ---NISALSSGLYQCV----------ASNAIGT----------STCLLDLQVISP--------QP 287
               .|...|.|.|...          ..||..|          :|.:|.|:|.|.        :.
  Fly   337 QPMPIRCESWGSYPAAKITWLLDGEPIRNAEVTVHSDKEDGNITTSILTLKVTSENDNAELTCRA 401

Human   288 RNIGLIAGAIGTGAVIIIF---CIALILGAFFYWRSKNKE-------EEEEEIPNEIREDDLPPK 342
            .|.....|||....:|.:.   .:::.|.        |::       .|.:.:..:.|.|..||.
  Fly   402 TNPWFSGGAIEDKRIIRVAYPPTVSVHLA--------NEDPSRLVTRAEGQNVTFKCRADARPPV 458

Human   343 CS--------------------------SAKAFHTEISSSDNNTLTSSNAYNSRYWSNNPKVHRN 381
            .|                          ||.|:....::::..|.:||.....::   :|:....
  Fly   459 TSYSWFKNGMRMSGESTEIMHLTQLERESAGAYACGATNTEGETRSSSLTLKVQF---SPRCKSG 520

Human   382 TESVSHFSDLGQSFSFHS------GNANIP-SIYANGTHLVPGQHKTLVVTANRGSSPQVMSR-- 437
            ||..|    :| :.|.||      .:|:.| |:..:.|:           ...|..||.:.||
  Fly   521 TEQTS----IG-AVSLHSILVKCEVDADPPDSVRFSWTY-----------NNTRNVSPVLNSRIQ 569

Human   438 SNGSVSRKPRPPHTHSYTISHA 459
            |||..|.....|.|.|..|:.|
  Fly   570 SNGLASTVTYLPQTDSELITLA 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IGSF11	NP_001340247.1	V-set	77..191	CDD:311561	32/130 (25%)
		Ig_3	208..269	CDD:316449	22/128 (17%)
side	NP_001247334.1	V-set	95..211	CDD:284989	34/153 (22%)
		IG_like	100..211	CDD:214653	33/148 (22%)
		Ig	235..301	CDD:299845	13/65 (20%)
		Ig	326..408	CDD:299845	13/81 (16%)
		IG_like	329..407	CDD:214653	13/77 (17%)
		IG_like	435..511	CDD:214653	12/75 (16%)
		Ig_2	442..511	CDD:290606	12/68 (18%)
		FN3	<700..735	CDD:238020

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910