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Protein Alignment IGSF11 and kirre

DIOPT Version :9

Sequence 1:	NP_001340247.1	Gene:	IGSF11 / 152404	HGNCID:	16669	Length:	481	Species:	Homo sapiens
Sequence 2:	NP_001245505.1	Gene:	kirre / 31292	FlyBaseID:	FBgn0028369	Length:	956	Species:	Drosophila melanogaster

Alignment Length:	532	Identity:	104/532 - (19%)
Similarity:	171/532 - (32%)	Gaps:	189/532 - (35%)

- Green bases have known domain annotations that are detailed below.

Human    66 YPSVAASLEVSESPGSI-----------QVARGQPAVLPC----------------------TFT 97
            |.|....|||..:|..|           ::..|...:|.|                      .||
  Fly   278 YRSAKLLLEVKYAPKVIVSVVGGALAGGKIPEGAEVILSCQADANPHELSYRWFINDELMTGDFT 342

Human    98 TSAALINLNVIW--------MVTPLSNANQPEQVILYQGGQMFDGAPRFHGR-------VGFTGT 147
            |...:.|::..:        :|..:..:.|.:::.:..|       |.|..|       :|.|.:
  Fly   343 TKMIIHNVSRQYHDAIVKCEVVNAVGKSEQSKKLDISFG-------PVFRQRPVSVEADLGATVS 400

Human   148 M-------PATNVS-IFINNTQL------------SDT-GTYQC--LVNNLPDIGGRNIGVTGLT 189
            |       |...:. |..|:.|:            |:| |.|.|  :||..|:||..       .
  Fly   401 MRCDVAGNPEPEIEWISENSDQVVGVAAELKLKVSSETAGRYFCKAVVNGFPEIGAE-------A 458

Human   190 VLVPPSAP-----HCQIQGSQDIGSDVILLCSSEEGIPRPTY-LWE---KLDNTLKLPPTA---- 241
            .|....||     ..|..|   :|..|.:.|.: ..||:..: ||.   |:.|.....|..
  Fly   459 TLYVKRAPIITSHKVQFGG---VGGRVKIDCLA-FSIPKAEHILWSFEGKIINMSSADPDIYIFE 519

Human   242 ---TQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNIGLIAGAIGTGAVI 303
               ..:.|:..:.||:..|...|.|.|...|:.|..:.::.|   ..:|.||.::...:|:
  Fly   520 EHHLPEGVRAALIIRDSKATHFGKYNCTVMNSYGGDSLVITL---LREPGNIPVLLVVMGS---- 577

Human   304 IIFCIALILG------AFFYWRSKNKEEEEEEIPNEIREDDLPPKCSS---AKAFHTEISSSDNN 359
             :||:|:||.      .:...||:.|....:.||...|..|...:..|   :||:..|.|.:..:
  Fly   578 -MFCVAIILMIVMIIIVYRKRRSRKKPMPADVIPEASRGGDKLNELKSELRSKAYDVEYSEAGGD 641

Human   360 ----TLTSS--------------------------------NAYNSRYWSNNPKVHRNT------ 382
                .||.|                                :.||.:....|.|..:.|
  Fly   642 GLAINLTQSPMPDVQMKGATLGVPLAGPVKFDERFSGDFGGDRYNRQCHIKNLKNQQETAYKGSP 706

Human   383 --ESVSHFSDLGQSFSFHSGNANIPSIYANGTHLVPGQHKTLVVTANRGSSPQVMSRSNGSVSRK 445
              ...:|:.:....:|                  .||.....||..:.|    |....||.:: .
  Fly   707 QANGYAHYFEYALDYS------------------PPGGEGAAVVVGSGG----VGKLKNGGMN-S 748

Human   446 PRPPHTHSYTIS 457
            ...||:.:.|::
  Fly   749 ATLPHSAAATVN 760

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.