Protein Alignment IGSF11 and igcm-4

DIOPT Version :9

• Sequence 1: NP_001340247.1
• Gene: IGSF11 / 152404
• HGNCID: 16669
• Length: 481
• Species: Homo sapiens
• Sequence 2: NP_508377.1
• Gene: igcm-4 / 180518
• WormBaseID: WBGene00022418
• Length: 541
• Species: Caenorhabditis elegans
• Alignment Length: 411
• Identity: 81/411 - (19%)
• Similarity: 137/411 - (33%)
• Gaps: 122/411 - (29%)

Human    82 IQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQVILY-QGGQMFDGAPRFHGRVGFT 145
            ::.|||.|..:....|.....:......:|.|:....:...:|.: :.|:..|...::
 Worm    26 VEAARGMPPRMRNVETKFRIPLGQKQFRLVCPIIATEKDSTMIQWSKNGEQLDWDSQY------- 83

Human   146 GTMPATNVSIFINNTQLSDTGTYQCLVNN------------LPDIGGRNIGVTGLTVLVPPSA-P 197
             .:...:..:.:.:.:..|:|.|||...|            :.|...:...|....||...:| |
 Worm    84 -KLSKDSKELKMKSVKFEDSGRYQCQATNGFGHKTIEFIVHVHDQHDKENSVKDYLVLSNTTASP 147

Human   198 HCQIQGSQD--------IGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRN 254
            ...|..:.:        .|..:.|.|.: :|.|.|...|  ..|.::: ...|...| .|:|:..
 Worm   148 SWLIDMNSEWRSPIKINTGGKLELRCPA-QGNPLPEIRW--YQNEMEI-SEKTHKHV-STITVEP 207

Human   255 ISALSSGLYQCVASNAIGTSTCLLDLQV---------------------ISPQPRNIGLIAGAIG 298
            :.:..||:|:||..|.:|:.:...|:.|                     :..||.||.:.||..
 Worm   208 VESSHSGVYRCVVENPLGSLSFAFDVSVGDFFDPTTTEATEYQETAMEPVIDQPYNISVYAGHT- 271

Human   299 TGAVIIIFCIALILGAFFYWRSKNKEE------EEEEIPNEIREDDLPPKCSSAKAFHTEISSSD 357
                           |.|..:.|:.|.      :|...|..||..|                  .
 Worm   272 ---------------AQFQCKVKSNENTIIKWLKEVSDPLSIRRKD------------------P 303

Human   358 NNTLTSSNAYNSRYWSNNPKVHRNTESVSHFSDLGQSFSFHSGNANIPSIYAN--GTHLVPGQHK 420
            |:|:...|..|.....     |..||     |.|.|.        ::.:||.|  ..|.|...|.
 Worm   304 NSTVIHVNGMNLLVLD-----HIQTE-----SSLPQE--------DMDNIYTNRLTIHKVDYHHA 350

Human   421 ---TLVVTANRGSSPQVMSRS 438
               ..|||:.:|   |::.:|
 Worm   351 GKYICVVTSAQG---QIVYKS 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IGSF11	NP_001340247.1	V-set	77..191	CDD:311561	18/121 (15%)
		Ig_3	208..269	CDD:316449	17/60 (28%)
igcm-4	NP_508377.1	IGc2	52..114	CDD:197706	11/69 (16%)
		I-set	159..235	CDD:254352	20/80 (25%)
		IGc2	166..225	CDD:197706	18/63 (29%)
		IG_like	261..373	CDD:214653	36/163 (22%)
		Ig	269..374	CDD:299845	32/155 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910