DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Foxj1 and FoxK

DIOPT Version :9

Sequence 1:	NP_032266.3	Gene:	Foxj1 / 15223	MGIID:	1347474	Length:	421	Species:	Mus musculus
Sequence 2:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster

Alignment Length:	305	Identity:	88/305 - (28%)
Similarity:	126/305 - (41%)	Gaps:	88/305 - (28%)

- Green bases have known domain annotations that are detailed below.

Mouse    53 PPGGTDPHGYHQVPGLVAPGSPLAADPACLGQPHTPGK-----PTSSCTSRSAPPG------LQA 106
            ||.|...|       |:|...|....|..:..|....|     ||.:.::.::.|.      :|.
  Fly   366 PPAGAAAH-------LIAGDGPGIYSPLKISIPKKEQKSPYLSPTGTISAANSCPASPRQGFIQN 423

Mouse   107 PP-----------------PDDVDYATNPHVKPPYSYATLICMAMQASKATKITLSAIYKWITDN 154
            .|                 |....|  |.:.|||||||.||..|:.|:...::|||.||.:|..:
  Fly   424 QPNNYNNYGNNNTQDLFQTPSTASY--NHNEKPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKH 486

Mouse   155 FCYFR-HADPTWQNSIRHNLSLNKCFIKVPREKDEPGKGGFWRIDPQYAERLLSGAFKKRRLPPV 218
            :.|:| ..:..||||||||||||:.||||.|.:||||||.||||||....:|:..::|||
  Fly   487 YPYYRKETNKGWQNSIRHNLSLNRYFIKVARSQDEPGKGSFWRIDPDSGAKLIDHSYKKR----- 546

Mouse   219 HIHPAFARQASQEPSAAPWGGPLTV--------NREAQQLLQE--FEEATGEGGWGTGE------ 267
                   ||.|.:....|:|.|.:.        |......||:  .:.|.|..|....:
  Fly   547 -------RQRSSQGFRPPYGMPRSAPVSPSHMDNSRESSPLQDIVLQSAPGSPGMSLEQRAADPE 604

Mouse   268 ----GRLGHKRKQPLPKRVAKVLRPPSTLLLTQEEQGELEPLKGN 308
                .:..|:::|                  .|::|.:.:.|..|
  Fly   605 IIYNSQNAHQQQQ------------------QQQQQQQQQTLSNN 631

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Foxj1	NP_032266.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..32
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	77..110		8/60 (13%)
		Forkhead	121..205	CDD:365978	48/84 (57%)
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	49/86 (57%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850