DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Foxq1 and FoxK

DIOPT Version :9

Sequence 1:	NP_032265.3	Gene:	Foxq1 / 15220	MGIID:	1298228	Length:	400	Species:	Mus musculus
Sequence 2:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster

Alignment Length:	259	Identity:	82/259 - (31%)
Similarity:	118/259 - (45%)	Gaps:	58/259 - (22%)

- Green bases have known domain annotations that are detailed below.

Mouse    10 AAH---GDKMG--SDLE-GAGSSDVPSP-LSAAGDDSLGSDGDCAANSPAAGSGAGDLEGGGGER 67
            |||   ||..|  |.|: .....:..|| ||..|..|       ||||..|....|.::......
  Fly   371 AAHLIAGDGPGIYSPLKISIPKKEQKSPYLSPTGTIS-------AANSCPASPRQGFIQNQPNNY 428

Mouse    68 NSSGGPSAQDGPEATDDSRTQASAAGPCAGGVGGGEGARSKPYTRRPKPPYSYIALIAMAIRDSA 132
            |:.|..:.|      |..:|.::|:                 |....||||||..||..||..:.
  Fly   429 NNYGNNNTQ------DLFQTPSTAS-----------------YNHNEKPPYSYAQLIVQAISAAP 470

Mouse   133 GGRLTLAEINEYLMGKFPFFR-GSYTGWRNSVRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPNS 196
            ..:|||:.|..:::..:|::| .:..||:||:|||||||..|:||.|....| ||.::|.::|:|
  Fly   471 DKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSLNRYFIKVARSQDEP-GKGSFWRIDPDS 534

Mouse   197 EYTFADGVFRRRRKRLSHRTTVSASGLRPEEAPPGPAGTPQPAPAARSSPIARSPARQEERSSP 260
            .....|..:::||:|       |:.|.||      |.|.|      ||:|::.|.......|||
  Fly   535 GAKLIDHSYKKRRQR-------SSQGFRP------PYGMP------RSAPVSPSHMDNSRESSP 579

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Foxq1	NP_032265.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..112		27/108 (25%)
		FH	115..193	CDD:238016	35/78 (45%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	213..264		14/48 (29%)
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	37/87 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820