Protein Alignment CTSZ and CG5367

DIOPT Version :9

• Sequence 1: NP_001327.2
• Gene: CTSZ / 1522
• HGNCID: 2547
• Length: 303
• Species: Homo sapiens
• Sequence 2: NP_609387.1
• Gene: CG5367 / 34401
• FlyBaseID: FBgn0032228
• Length: 338
• Species: Drosophila melanogaster
• Alignment Length: 280
• Identity: 76/280 - (27%)
• Similarity: 125/280 - (44%)
• Gaps: 64/280 - (22%)

Human    27 FRRGQTCYRPLRGDGLAPLGRSTYPRPHEYL-----------------SP--ADLPKSWDWRNVD 72
            ::.|||.:| |:.:..|.:....|.:....|                 ||  |::|:|.|||:..
  Fly    74 YKEGQTSFR-LKPNIFADMSTDGYLKGFLRLLKSNIEDSADNMAEIVGSPLMANVPESLDWRSKG 137

Human    73 GVNYASITRNQHIPQY----CGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDC----GNA 129
            .:.          |.|    ||||:|.:...::..:: .||.|...|  ||.|.::||    ||.
  Fly   138 FIT----------PPYNQLSCGSCYAFSIAESIMGQV-FKRTGKILS--LSKQQIVDCSVSHGNQ 189

Human   130 GSCEGGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYG 194
            | |.||:..:...|....|        ...:||:.....:.|.| :|....::.|.|.|.:
  Fly   190 G-CVGGSLRNTLSYLQSTG--------GIMRDQDYPYVARKGKC-QFVPDLSVVNVTSWAI---- 240

Human   195 SLSGREK--MMAEIYANGPISCGIMATERLAN-YTGGIYAE-YQDTTYINHVVSVAGWGISDGTE 255
             |..|::  :.|.:...||::..|.|:.:... |:.|||.: ...:..:||.:.|.|:    |.:
  Fly   241 -LPVRDEQAIQAAVTHIGPVAISINASPKTFQLYSDGIYDDPLCSSASVNHAMVVIGF----GKD 300

Human   256 YWIVRNSWGEPWGERGWLRI 275
            |||::|.||:.|||.|::||
  Fly   301 YWILKNWWGQNWGENGYIRI 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CTSZ	NP_001327.2	Peptidase_C1A_CathepsinX	62..302	CDD:239149	65/226 (29%)
CG5367	NP_609387.1	Inhibitor_I29	36..96	CDD:285458	6/22 (27%)
		Peptidase_C1A	128..336	CDD:239068	65/225 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820