Protein Alignment Hey1 and cwo

DIOPT Version :9

• Sequence 1: NP_034553.2
• Gene: Hey1 / 15213
• MGIID: 1341800
• Length: 299
• Species: Mus musculus
• Sequence 2: NP_524775.1
• Gene: cwo / 44669
• FlyBaseID: FBgn0259938
• Length: 698
• Species: Drosophila melanogaster
• Alignment Length: 400
• Identity: 84/400 - (21%)
• Similarity: 141/400 - (35%)
• Gaps: 135/400 - (33%)

Mouse     6 PDYSSSDSELDETIEVEKESA--------DENGNLSSALCSMSPTTSSQVLARKRRRG------- 55
            |.::.::......::.|.|:|        :.:.|.|::..:.|...:.....|:.:..
  Fly     3 PYWNETNGHAAHPVKYESEAAVSSFPYCTESSLNFSTSATAYSEDDAEYATGRRNKTSRQDPLSH 67

Mouse    56 -IIEKRRRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALA 119
             |||||||||:|:.|::|.||:|..::::|..::||.||::|.:.|||.|.:       :.....
  Fly    68 RIIEKRRRDRMNSCLADLSRLIPPQYQRKGRGRIEKTEIIEMAIRHLKHLQS-------ECQQKE 125

Mouse   120 MDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNN------YASQREAASGAHGGLGHI 178
            .|||| |:.:|:.|.|::|..:...|....|..||..|::.      |.|.|..         |:
  Fly   126 SDYRS-GYMDCMKEAAKFLYDVHMQDFCHRLLGRLQEHIDEMFKTDCYKSTRSC---------HM 180

Mouse   179 PWG-SAFGHHPHIA-HPLL---------------------------------------------- 195
            |.. ||....||.| ||.|
  Fly   181 PDNVSASSGSPHQAYHPPLCHLRDMLATSASDVEHSQDHNDVKDLSFRNHLNQLQRSQQAAAAAA 245

Mouse   196 -----------------------------------------LPQNGHGNAGTAASPTEPHHQGRL 219
                                                     :|.|..| :|:||:....:.....
  Fly   246 VAAAAVAVANGSSPASNAGVDSKVPLTNGGGTGGAPPAADNVPSNSTG-SGSAAACAGGNSNSSG 309

Mouse   220 ASAHPEAPALRAPPSGGLGP--VLPVVTSASKLSPPLLSSVASLSAFPFSFSSFH----LLSPST 278
            :::...|.:...||:||..|  |.|:.........|:::|.|.......:.||.|    ...|..
  Fly   310 SNSSNAASSTICPPAGGSCPAKVTPLAAHQQPHQAPVITSTAPHHHHHHTDSSHHDFESSREPIL 374

Mouse   279 PTQAANLGKP 288
            .|..:|:..|
  Fly   375 HTDTSNMHSP 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hey1	NP_034553.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..53		8/54 (15%)
		Transcriptional repression and interaction with NCOR1 and SIN3A. /evidence=ECO:0000250	48..117		26/76 (34%)
		HLH	50..107	CDD:238036	26/64 (41%)
		ORANGE	120..166	CDD:128787	16/51 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..234		9/126 (7%)
		YRPW motif	289..292		83/399 (21%)
cwo	NP_524775.1	HLH	66..118	CDD:306515	24/51 (47%)
		ORANGE	126..168	CDD:128787	14/42 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830920
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840