Protein Alignment Hey1 and h

DIOPT Version :9

• Sequence 1: NP_034553.2
• Gene: Hey1 / 15213
• MGIID: 1341800
• Length: 299
• Species: Mus musculus
• Sequence 2: NP_001014577.1
• Gene: h / 38995
• FlyBaseID: FBgn0001168
• Length: 337
• Species: Drosophila melanogaster
• Alignment Length: 341
• Identity: 77/341 - (22%)
• Similarity: 117/341 - (34%)
• Gaps: 133/341 - (39%)

Mouse    50 RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHTAGGKGY 112
            |:..:.|:|||||.||||.|:||:.|:..|.:|..:  :|||||:||:.||.||:.|........
  Fly    32 RRSNKPIMEKRRRARINNCLNELKTLILDATKKDPARHSKLEKADILEKTVKHLQELQRQQAAMQ 96

Mouse   113 FDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNN---------YASQREAA 168
            ..|....::....||.:|:.||:|:    .|::.:.  |.||:.||:|         :..||:
  Fly    97 QAADPKIVNKFKAGFADCVNEVSRF----PGIEPAQ--RRRLLQHLSNCINGVKTELHQQQRQ-- 153

Mouse   169 SGAHGGLGHIPWGSAFGHHPHIAHPLLLPQNGHGNAGTAASPTEPHHQGRLASAHP-------EA 226
                             ......|..:||          :.|:.|....:..:|.|       .|
  Fly   154 -----------------QQQQSIHAQMLP----------SPPSSPEQDSQQGAAAPYLFGIQQTA 191

Mouse   227 PALRAP----------PSGGLGPVLP---------------------------VVTSASKLSPPL 254
            .....|          |:|.:..|||                           ...:|::..|.|
  Fly   192 SGYFLPNGMQVIPTKLPNGSIALVLPQSLPQQQQQQLLQHQQQQQQLAVAAAAAAAAAAQQQPML 256

Mouse   255 LS--------------SVASLSAFPFSFSSFHLLSPS------------------TPTQAANLG- 286
            :|              |.|...:.|.|.||.....||                  .|.:...|.
  Fly   257 VSMPQRTASTGSASSHSSAGYESAPGSSSSCSYAPPSPANSSYEPMDIKPSVIQRVPMEQQPLSL 321

Mouse   287 ----------KPYRPW 292
                      :|:|||
  Fly   322 VIKKQIKEEEQPWRPW 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hey1	NP_034553.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..53		1/2 (50%)
		Transcriptional repression and interaction with NCOR1 and SIN3A. /evidence=ECO:0000250	48..117		30/68 (44%)
		HLH	50..107	CDD:238036	29/58 (50%)
		ORANGE	120..166	CDD:128787	14/54 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..234		8/56 (14%)
		YRPW motif	289..292		1/2 (50%)
h	NP_001014577.1	HLH	29..88	CDD:238036	28/55 (51%)
		ORANGE	106..141	CDD:128787	13/40 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810