DRSC/TRiP Functional Genomics Resources

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Protein Alignment Hey1 and dpn

DIOPT Version :9

Sequence 1:NP_034553.2 Gene:Hey1 / 15213 MGIID:1341800 Length:299 Species:Mus musculus
Sequence 2:NP_476923.1 Gene:dpn / 35800 FlyBaseID:FBgn0010109 Length:435 Species:Drosophila melanogaster


Alignment Length:321 Identity:95/321 - (29%)
Similarity:142/321 - (44%) Gaps:61/321 - (19%)


- Green bases have known domain annotations that are detailed below.


Mouse     7 DYS---SSDSELDETIEVEKESADENGNLSSALCSMSPTTSSQVLARKRRRGIIEKRRRDRINNS 68
            ||.   :||.:.| ......:|...||.:|      :|...|:...||..:.|:|||||.|||:.
  Fly     2 DYKNDINSDDDFD-CSNGYSDSYGSNGRMS------NPNGLSKAELRKTNKPIMEKRRRARINHC 59

Mouse    69 LSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAMDYRSLGFRECL 131
            |:||:.|:..|.:|..:  .|||||:||:|||.||:.:..........:....:.....||.||.
  Fly    60 LNELKSLILEAMKKDPARHTKLEKADILEMTVKHLQSVQRQQLNMAIQSDPSVVQKFKTGFVECA 124

Mouse   132 AEVARYLSIIEGLDASDPLRVRLVSHLNNYASQREA-------ASGAHGGLGHIPWGSAFGHHPH 189
            .||.||:|.::|:|..  :|.||.:|||..|:..|.       ::|..|||  .| .:|....|.
  Fly   125 EEVNRYVSQMDGIDTG--VRQRLSAHLNQCANSLEQIGSMSNFSNGYRGGL--FP-ATAVTAAPT 184

Mouse   190 IAHPLLLPQNGHGNAGTAASPTEPHHQGRLASAHPEAPALRAP---------PSGGLGPVLPVVT 245
            ...| .|||:.:.|:.|.:|                |||::..         |||....::|...
  Fly   185 PLFP-SLPQDLNNNSRTESS----------------APAIQMGGLQLIPSRLPSGEFALIMPNTG 232

Mouse   246 SASKLSPPLL--SSVASLSAFPFSFSSFHLLSPSTPTQAANLGKPYR------PWGTEIGA 298
            ||:....|..  .|.|.::|   ..:|..|.|.:.||...:..:.:|      |..|.:.|
  Fly   233 SAAPPPGPFAWPGSAAGVAA---GTASAALASIANPTHLNDYTQSFRMSAFSKPVNTSVPA 290

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Hey1NP_034553.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..53 13/48 (27%)
Transcriptional repression and interaction with NCOR1 and SIN3A. /evidence=ECO:0000250 48..117 29/70 (41%)
HLH 50..107 CDD:238036 29/58 (50%)
ORANGE 120..166 CDD:128787 18/45 (40%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 194..234 9/48 (19%)
YRPW motif 289..292 1/8 (13%)
dpnNP_476923.1 HLH 39..101 CDD:238036 29/61 (48%)
ORANGE 114..158 CDD:128787 18/45 (40%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4304
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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