Protein Alignment CTSW and CG5367

DIOPT Version :9

• Sequence 1: NP_001326.3
• Gene: CTSW / 1521
• HGNCID: 2546
• Length: 376
• Species: Homo sapiens
• Sequence 2: NP_609387.1
• Gene: CG5367 / 34401
• FlyBaseID: FBgn0032228
• Length: 338
• Species: Drosophila melanogaster
• Alignment Length: 377
• Identity: 97/377 - (25%)
• Similarity: 153/377 - (40%)
• Gaps: 69/377 - (18%)

Human     9 CLLAL----LVAGLAQGIRGPLRAQDLGPQPLELKEAFKLFQIQFNRSYLSPEEHAHRLDIFAHN 69
            ||..|    :.:.|::|          .......|..|:.|:...||.||...:.......|..|
  Fly     9 CLCGLNCQIVTSNLSEG----------NSSSANCKSEFEKFKNNNNRKYLRTYDEMRSYKAFEEN 63

Human    70 L----AQAQRLQEEDLGTAEFGVTP--FSDLTEEEFGQLYGYRR-----AAGGVPSMGREIRSEE 123
            .    ...|..:|   |...|.:.|  |:|::.:  |.|.|:.|     ......:|. ||....
  Fly    64 FKVIEEHNQNYKE---GQTSFRLKPNIFADMSTD--GYLKGFLRLLKSNIEDSADNMA-EIVGSP 122

Human   124 PEESVPFSCDWRKVASAISPIKDQKNCNCCWAMAAAGNI--ETLWRISFWDFVDVSVQELLDC-- 184
            ...:||.|.|||. ...|:|..:|.:|..|:|.:.|.:|  :...|..  ..:.:|.|:::||
  Fly   123 LMANVPESLDWRS-KGFITPPYNQLSCGSCYAFSIAESIMGQVFKRTG--KILSLSKQQIVDCSV 184

Human   185 GRCGDGCHGGFVWDAFITVLNNSGLASEKDYPFQGKVRAHRCHPKKYQKVAWIQDFIMLQNNEHR 249
            .....||.||.:.:....:.:..|:..::|||:  ..|..:|.......|..:..:.:|...:.:
  Fly   185 SHGNQGCVGGSLRNTLSYLQSTGGIMRDQDYPY--VARKGKCQFVPDLSVVNVTSWAILPVRDEQ 247

Human   250 IAQYLATY-GPITVTINMKP--LQLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAET 311
            ..|...|: ||:.::||..|  .|||..|:.  ....|....|:|:::::|||.
  Fly   248 AIQAAVTHIGPVAISINASPKTFQLYSDGIY--DDPLCSSASVNHAMVVIGFGK----------- 299

Human   312 VSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRGSNTCGITKFPLTARV 363
                         .||||||.||..|||.||.|:.:|.|.|||..:...|.|
  Fly   300 -------------DYWILKNWWGQNWGENGYIRIRKGVNMCGIANYAAYAIV 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CTSW	NP_001326.3	Inhibitor_I29	42..98	CDD:214853	15/61 (25%)
		Peptidase_C1A	129..358	CDD:239068	66/235 (28%)
CG5367	NP_609387.1	Inhibitor_I29	36..96	CDD:285458	15/64 (23%)
		Peptidase_C1A	128..336	CDD:239068	66/238 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12411
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910