Protein Alignment Hes3 and E(spl)mbeta-HLH

DIOPT Version :9

• Sequence 1: XP_011248491.1
• Gene: Hes3 / 15207
• MGIID: 104877
• Length: 291
• Species: Mus musculus
• Sequence 2: NP_524505.2
• Gene: E(spl)mbeta-HLH / 43152
• FlyBaseID: FBgn0002733
• Length: 195
• Species: Drosophila melanogaster
• Alignment Length: 200
• Identity: 62/200 - (31%)
• Similarity: 87/200 - (43%)
• Gaps: 40/200 - (20%)

Mouse   112 ISKPLMEKKRRARINVSLEQLRSL----LERHYSHQIRKRKLEKADILELSVKYMRSLQNSLQ-G 171
            :.||::|:|||||||..|::|:.:    |.:...|..|   |||||||||:|::|:.|:...| .
  Fly    16 VMKPMLERKRRARINKCLDELKDIMVECLTQEGEHITR---LEKADILELTVEHMKKLRAQKQLR 77

Mouse   172 LWPVPSGV------------DYPSGFQGGLRGVSQRLR--PGEG-DSGLRCPLLLQRREGSTTDS 221
            |..|..||            .:.:|:......||:.|.  ||.. |.|.:....|..|
  Fly    78 LSSVTGGVSPSADPKLSIAESFRAGYVHAANEVSKTLAAVPGVSVDLGTQLMSHLGHR------- 135

Mouse   222 ANPQATSVLNPCLPAIWAPSRAAGGSHSPQSPLPLPGGLLESSTDVVAPHPASNCQAESTRPGFR 286
              .....|:.|.|| |..|.:|.....:..:|.|.....|||.....||..||:....
  Fly   136 --LNYLQVVVPSLP-IGVPLQAPVEDQAMVTPPPSECDSLESGACSPAPSEASSTSGP------- 190

Mouse   287 VWRPW 291
            :||||
  Fly   191 MWRPW 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hes3	XP_011248491.1	bHLH-O_HES3	117..171	CDD:381503	26/58 (45%)
E(spl)mbeta-HLH	NP_524505.2	HLH	13..75	CDD:238036	27/61 (44%)
		ORANGE	97..141	CDD:128787	10/52 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830847
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840