Protein Alignment CTSS and CG5367

DIOPT Version :9

• Sequence 1: NP_004070.3
• Gene: CTSS / 1520
• HGNCID: 2545
• Length: 331
• Species: Homo sapiens
• Sequence 2: NP_609387.1
• Gene: CG5367 / 34401
• FlyBaseID: FBgn0032228
• Length: 338
• Species: Drosophila melanogaster
• Alignment Length: 314
• Identity: 108/314 - (34%)
• Similarity: 167/314 - (53%)
• Gaps: 33/314 - (10%)

Human    31 WKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMS----- 90
            :|....::|....:|......:|:|.|.:..||..:..|..|:.|..|...||:::..:.
  Fly    39 FKNNNNRKYLRTYDEMRSYKAFEENFKVIEEHNQNYKEGQTSFRLKPNIFADMSTDGYLKGFLRL 103

Human    91 LMSSLR---------VPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVG 146
            |.|::.         |.|....|:          |:|:|||.||.:|....|.|||:|:|||...
  Fly   104 LKSNIEDSADNMAEIVGSPLMANV----------PESLDWRSKGFITPPYNQLSCGSCYAFSIAE 158

Human   147 ALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQ 211
            ::..|:..:|||::|||.|.:||||. .:||:||.||.:.....|:....||..|..|||.|...
  Fly   159 SIMGQVFKRTGKILSLSKQQIVDCSV-SHGNQGCVGGSLRNTLSYLQSTGGIMRDQDYPYVARKG 222

Human   212 KCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQ-N 275
            |||:.........:.:..||...|..::.||.:.|||::.::|...:|.||..|:|.:|.|:. :
  Fly   223 KCQFVPDLSVVNVTSWAILPVRDEQAIQAAVTHIGPVAISINASPKTFQLYSDGIYDDPLCSSAS 287

Human   276 VNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKG-NHCGIASFPSY 328
            |||.::|:|:    ||:||::||.||.|:||.||||:  .|| |.||||::.:|
  Fly   288 VNHAMVVIGF----GKDYWILKNWWGQNWGENGYIRI--RKGVNMCGIANYAAY 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CTSS	NP_004070.3	PTZ00203	5..326	CDD:185513	107/310 (35%)
		Inhibitor_I29	28..87	CDD:214853	14/55 (25%)
		Peptidase_C1	115..329	CDD:278538	89/216 (41%)
CG5367	NP_609387.1	Inhibitor_I29	36..96	CDD:285458	14/56 (25%)
		Peptidase_C1A	128..336	CDD:239068	89/215 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.830