Protein Alignment UPP2 and CG3788

DIOPT Version :10

• Sequence 1: NP_001128570.1
• Gene: UPP2 / 151531
• HGNCID: 23061
• Length: 374
• Species: Homo sapiens
• Sequence 2: NP_611738.1
• Gene: CG3788 / 37644
• FlyBaseID: FBgn0034800
• Length: 378
• Species: Drosophila melanogaster
• Alignment Length: 348
• Identity: 142/348 - (40%)
• Similarity: 217/348 - (62%)
• Gaps: 23/348 - (6%)

Human    40 SHASCTACGTVTFHIVERMASVIPASNRSM---------------RSDRNTYVGKRFVHVKNPYL 89
            |.::|:.|.....:.|.::.:::.|.:|::               .:..:|..|      .||.|
  Fly     2 SKSNCSDCTCRLANEVGQLKAIVNAQSRTLAKLVRQMKEGCKKDEEAKESTLCG------LNPCL 60

Human    90 DLMDEDILYHLDLGTKTHNLPAMFGDVKFVCVGGSPNRMKAFALFMHKELGFE-EAEEDIKDICA 153
            ..:..||||||.|.|:|.:.|.:||||:|||:||:|.||:.||.::.:|:|.: .|...:::|..
  Fly    61 KCLQPDILYHLGLNTETTDFPKVFGDVRFVCMGGTPGRMENFAYYVMQEIGLKINAATKLRNISE 125

Human   154 GTDRYCMYKTGPVLAISHGMGIPSISIMLHELIKLLHHARCCDVTIIRIGTSGGIGIAPGTVVIT 218
            ...|:.::|.||||..|||||.|||||:||||||:::||:|.|...||||||||||:.||||:|:
  Fly   126 AGQRFSLFKVGPVLCASHGMGCPSISILLHELIKMMYHAKCKDPVFIRIGTSGGIGVEPGTVIIS 190

Human   219 DIAVDSFFKPRFEQVILDNIVTRSTELDKELSEELFNCSKEIPN-FPTLVGHTMCTYDFYEGQGR 282
            ..|:|....|..|.::....|..:::||:.|::|:..|.....: :..::|.|:|.:||||||.|
  Fly   191 SEAIDGRLNPVHEILVHGVSVQHASQLDESLADEIKMCHDPCKDKYEAVIGRTLCAHDFYEGQSR 255

Human   283 LDGALCSFSREKKLDYLKRAFKAGVRNIEMESTVFAAMCGLCGLKAAVVCVTLLDRLDCDQINLP 347
            ||||.|.::.|.|..||:......|:||||||..|||:.....::.|||||.:|:||:.|||..|
  Fly   256 LDGAFCEYTPEMKKSYLETLQSQQVKNIEMESLAFAALTSRANIRGAVVCVAILNRLNGDQIKTP 320

Human   348 HDVLVEYQQRPQLLISNFIRRRL 370
            ||||.::::|||.|::.:||:.|
  Fly   321 HDVLSKWEKRPQELVARYIRKVL 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UPP2	NP_001128570.1	UP_hUPP-like	94..368	CDD:350163	129/275 (47%)
CG3788	NP_611738.1	euk_UDPppase	57..345	CDD:130780	134/287 (47%)