Protein Alignment CTSV and Swim

DIOPT Version :9

• Sequence 1: NP_001188504.1
• Gene: CTSV / 1515
• HGNCID: 2538
• Length: 334
• Species: Homo sapiens
• Sequence 2: NP_611652.2
• Gene: Swim / 37537
• FlyBaseID: FBgn0034709
• Length: 431
• Species: Drosophila melanogaster
• Alignment Length: 247
• Identity: 82/247 - (33%)
• Similarity: 116/247 - (46%)
• Gaps: 37/247 - (14%)

Human   114 LPKSVD----WRKKGYVTPVKNQKQCGSCWAFSATGALEGQM-FRKTGK-LVSLSEQNLVDCSRP 172
            ||.|.:    |  ..|::.|.:|..||:.|..|.|.....:. .:..|| .|.||.||::.|:|.
  Fly   187 LPSSFNALDKW--SSYISEVPDQGWCGASWVLSTTSVASDRFAIQSKGKENVQLSAQNILSCTRR 249

Human   173 QGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYR-------------PENSVANDTG 224
            |  |||.||.:..|::|:.:.|.:| |..|||....:.||.|             |.| |..|:.
  Fly   250 Q--QGCEGGHLDAAWRYLHKKGVVD-ENCYPYTQHRDTCKIRHNSRSLRANGCQKPVN-VDRDSL 310

Human   225 FTV---VAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLD--HGVLVVGY 284
            :||   .:..:|..:|..:...||:...|......|. |..|:|.|...:.|...  |.|.:||:
  Fly   311 YTVGPAYSLNREADIMAEIFHSGPVQATMRVNRDFFA-YSGGVYRETAANRKAPTGFHSVKLVGW 374

Human   285 GFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIA--TAASYPNV 334
            |.|   .|..|||:..||||..||.:||.:|.:. :|.|||.  ..||:|.|
  Fly   375 GEE---HNGEKYWIAANSWGSWWGEHGYFRILRG-SNECGIEEYVLASWPYV 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CTSV	NP_001188504.1	Inhibitor_I29	29..87	CDD:214853
		Peptidase_C1	114..332	CDD:306594	80/243 (33%)
Swim	NP_611652.2	Somatomedin_B	41..83	CDD:279385
		VWC	91..>126	CDD:302663
		Peptidase_C1A_CathepsinB	188..417	CDD:239111	77/239 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149687
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840