Protein Alignment CTSV and cpl-1

DIOPT Version :10

• Sequence 1: NP_001324.2
• Gene: CTSV / 1515
• HGNCID: 2538
• Length: 334
• Species: Homo sapiens
• Sequence 2: NP_001256718.1
• Gene: cpl-1 / 180111
• WormBaseID: WBGene00000776
• Length: 337
• Species: Caenorhabditis elegans
• Alignment Length: 340
• Identity: 159/340 - (46%)
• Similarity: 214/340 - (62%)
• Gaps: 9/340 - (2%)

Human     1 MNLSLVLAAFCLGIASAVPKFDQNLDT---KWYQWKATHRRLYGANEEGWRRAVWEKNMKMIELH 62
            ||..::||.....:|....|..:.:::   ||..:|....:.|..:||......:.|||..||.|
 Worm     1 MNRFILLALVAAVVAVNSAKLSRQIESAIEKWDDYKEDFDKEYSESEEQTYMEAFVKNMIHIENH 65

Human    63 NGEYSQGKHGFTMAMNAFGDMTNEEFRQMMG---CFRNQKFRKGKVFREPLFLDLPKSVDWRKKG 124
            |.::..|:..|.|.:|...|:...::|::.|   .|.:.:.:....|..|..:.:|..||||...
 Worm    66 NRDHRLGRKTFEMGLNHIADLPFSQYRKLNGYRRLFGDSRIKNSSSFLAPFNVQVPDEVDWRDTH 130

Human   125 YVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQY 189
            .||.||||..||||||||||||||||..||.|:|||||||||||||...||.|||||.|.:||:|
 Worm   131 LVTDVKNQGMCGSCWAFSATGALEGQHARKLGQLVSLSEQNLVDCSTKYGNHGCNGGLMDQAFEY 195

Human   190 VKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGH 254
            :::|.|:|:||||||...|..|.:..:...|:|.|:.....|.|:.|..||||.||||:|:||||
 Worm   196 IRDNHGVDTEESYPYKGRDMKCHFNKKTVGADDKGYVDTPEGDEEQLKIAVATQGPISIAIDAGH 260

Human   255 SSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDK 319
            .|||.||.|:|::.:|||:.||||||:|||   |.:..:..||:||||||..||..||::||:::
 Worm   261 RSFQLYKKGVYYDEECSSEELDHGVLLVGY---GTDPEHGDYWIVKNSWGAGWGEKGYIRIARNR 322

Human   320 NNHCGIATAASYPNV 334
            |||||:||.||||.|
 Worm   323 NNHCGVATKASYPLV 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CTSV	NP_001324.2	Inhibitor_I29	29..87	CDD:214853	17/57 (30%)
		Peptidase_C1	114..332	CDD:425470	127/217 (59%)
cpl-1	NP_001256718.1	Inhibitor_I29	32..91	CDD:462410	17/58 (29%)
		Peptidase_C1	120..336	CDD:425470	128/218 (59%)