Protein Alignment SLC16A14 and kar

DIOPT Version :10

• Sequence 1: NP_689740.2
• Gene: SLC16A14 / 151473
• HGNCID: 26417
• Length: 510
• Species: Homo sapiens
• Sequence 2: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Alignment Length: 478
• Identity: 113/478 - (23%)
• Similarity: 199/478 - (41%)
• Gaps: 86/478 - (17%)

Human    29 DGG-WAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEF-----HQSRGLTAWVSSLSMGITLIVG 87
            ||| .||::::|:|..:.:|.|.....||::....:..     .::....|.:.:|::|.|.:..
  Fly    75 DGGARAWLVMVSAFLCNGIIFGFINTYGVIHSLLTDRLTKLGDPEASSKAALIGALAIGTTFLFS 139

Human    88 PFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAA-NVHYLFITFGVAAGLGSGMAYLPAVVMVGR 151
            ...|...:..|.|.|...||::::.|.:||::.. |:..|:.|:|:..|||:.:||.|.:.::|.
  Fly   140 TMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYTPTLAILGH 204

Human   152 YFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMLIQGAVSLNLCVCGALMRPLSPGK 216
            ||::......|..|.|:...|.::...|..|...||....:.|...||..:.:|..:.:||.|
  Fly   205 YFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFIILCSFVYKPLHP-- 267

Human   217 NPNDPGEKDVRGLPAHSTESVKSTGQQGRTEEKDGGLGNEETLCDLQAQECPDQAGHRKNMCALR 281
             |.:|.:|                 :.||:                           |.|:....
  Fly   268 -PPEPPKK-----------------KPGRS---------------------------RINLFLRS 287

Human   282 ILKTVSWLTMRVRKGFEDWYSGYFGTASLFTNRMFVAFIFWAL---FAYSSFVIPFIHLPEIVNL 343
            |:....|...|                          |:.|||   .|...:.:|::|:.:.|..
  Fly   288 IINVEIWKRKR--------------------------FVIWALCVPLALFGYFVPYVHMMQFVKT 326

Human   344 YNLSEQNDVFPLTSIIAIVHIFGKVILGVIADLPCISVWNVFLLANFTLVLSIFILPLMHTYAGL 408
            ....|  ||......|.|....|::|.|||||:|.::...:..|:..::.|...:|||.::|..|
  Fly   327 TFPGE--DVNLPVMCIGITSGIGRLIFGVIADMPGVNRMYLQQLSLVSIGLVTLLLPLTNSYVIL 389

Human   409 AVICALIGFSSGYF-SLMPVVTEDLVGIEHLANAYGIIICANGISALLGPPFAGWIYDITQKYDF 472
            .....::|...|.| ||:..:..::.|......|.|.::..:.|...:|||.||.|:|.|..|..
  Fly   390 VSFTLVMGLFDGCFISLLGPIAYEICGPSGATQAIGFLLGLSSIPLTVGPPVAGMIFDSTNSYTL 454

Human   473 SFYICGLLYMIGILFLLIQPCIR 495
            ...:.||..::|...|.:..|::
  Fly   455 PLILAGLPPLLGSSLLFLIKCVK 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC16A14	NP_689740.2	MFS_MCT14	33..492	CDD:340987	109/468 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..255		6/40 (15%)
kar	NP_001189213.1	MFS_MCT8_10	80..474	CDD:340978	109/468 (23%)