Protein Alignment SLC16A14 and CG8389

DIOPT Version :10

• Sequence 1: NP_689740.2
• Gene: SLC16A14 / 151473
• HGNCID: 26417
• Length: 510
• Species: Homo sapiens
• Sequence 2: NP_611076.2
• Gene: CG8389 / 36764
• FlyBaseID: FBgn0034063
• Length: 471
• Species: Drosophila melanogaster
• Alignment Length: 483
• Identity: 107/483 - (22%)
• Similarity: 191/483 - (39%)
• Gaps: 81/483 - (16%)

Human    29 DGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMGITLIVGPFIGLF 93
            |||:.|::|.:...:::.........|.|.|..|::..:.....|.:::|:.......|.|||..
  Fly    11 DGGYGWIVVAAVALINMTNQSILSVFGQLFVGELQKMQEDTFTAALITNLNSLALNFSGLFIGPA 75

Human    94 INTCGCRQTAIIGGLVNSLGWVLSAYAANVHYLFITFGVAAGLGSGMAYLPAVVMVGRYFQKRRA 158
            |.:...|..|..|.::.:||..|.|:|:...:..:.:....|.|.|:......:.:..||..:|.
  Fly    76 IKSFKPRNVAATGCILVALGLALCAFASESWHFILGYSFFVGFGLGLISPSTFMAINSYFTTKRG 140

Human   159 LAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMLIQGAVSLNLCVCGALMRPLSPGKNPNDPGE 223
            .|.|:|..|.|.|..|:..|::||...:|:|.|:|...::||......|.::||:|....|:  .
  Fly   141 RAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLFGLFGAAFLKPLNPPAKHNN--R 203

Human   224 KDVR------GLPAHSTESVKSTGQQGRTEEKDGGLGNEETLCDLQAQECPDQAGHRKNMCALRI 282
            |.:|      |......:.|.....|.:.|...   .|.:|||....|
  Fly   204 KHIRLLTEADGEKTSPLQVVIVPTNQSKIERSP---PNVDTLCSRMGQ----------------- 248

Human   283 LKTVSWLTMRVRKGFEDWYSGYFGTASLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVNLYNLS 347
             :.|..:.:.:.|....| |...|.|.::|..:....||......::               .|:
  Fly   249 -RLVQAMDLELLKDLVFW-SIIVGMALVYTATINFTMIFPGFLGQTA---------------QLN 296

Human   348 EQNDVFPLTSIIAIVHIFGKVILGVIADLPCISVWNVFLLANFTLVLSIFI----------LPLM 402
            .|...|.: |::|...|..:::|.::.|...|....|||:.    ::.:|:          ||::
  Fly   297 SQMVAFCM-SLVAGADIVFRLLLPIVTDHLRIPYRVVFLIG----IVGLFVARCVLAENQTLPVI 356

Human   403 HTYAGLAVICALIGFSSGYFSLMPVVTEDLVGIEH-----LANAYGIIICANGISALLGPPFAGW 462
            .|.:.|          :|......|:..:|....|     ||...|:.:.:.|:..:......||
  Fly   357 ITMSVL----------TGMMKSATVINNNLTISAHCRSEKLAGGLGLSMMSKGVIVITVGQLLGW 411

Human   463 IYDITQKYDFSFYICGLLYMIGILFLLI 490
            :.|    |..|:.||  ||..|::.|::
  Fly   412 VRD----YADSYLIC--LYAQGVILLVV 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC16A14	NP_689740.2	MFS_MCT14	33..492	CDD:340987	104/479 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..255		8/46 (17%)
CG8389	NP_611076.2	MFS_MCT_SLC16	15..440	CDD:340910	104/479 (22%)