Protein Alignment SLC16A14 and CG10019

DIOPT Version :10

• Sequence 1: NP_689740.2
• Gene: SLC16A14 / 151473
• HGNCID: 26417
• Length: 510
• Species: Homo sapiens
• Sequence 2: NP_001368939.1
• Gene: CG10019 / 33600
• FlyBaseID: FBgn0031568
• Length: 1159
• Species: Drosophila melanogaster
• Alignment Length: 547
• Identity: 118/547 - (21%)
• Similarity: 215/547 - (39%)
• Gaps: 115/547 - (21%)

Human     3 TSHEDIGYDFEDGPKDKKTLKPHPNI-------------------DGGWAWMMVLSSFFVHILIM 48
            |..||..:   .|..|::....|.||                   ||||.|::...||.||||..
  Fly   398 TDEEDSAF---PGLADREFHLLHRNIPALRRTGVDTTRIRQYFYPDGGWGWIICGVSFLVHILTT 459

Human    49 GSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLG 113
            |.|::.|:|....::..|.:.|:.. :.:||..::::...|:.........|..:|:||||..||
  Fly   460 GLQLSYGLLWFYAVQYLHNTSGIEL-LGALSWSVSMVATSFVVSLCRKRSIRLLSIVGGLVMPLG 523

Human   114 WVLSAYAANVHYLFITFGVAAGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVL 178
            .:.:::|.....:..::|:..|:|..|....:.||:|.||::||...:.::.:|.|.|..|.:|:
  Fly   524 ILFTSFATEFGQVVFSYGIVFGVGVAMVREASTVMLGNYFKRRRQFVEMVAMSGEGVGIALFSVI 588

Human   179 LKYLCAEYGWRNAMLIQGAVSLNLCVCGALMRPLSPGKNPNDPGEKDVRGLPAHSTESVKSTGQQ 243
            ||....:.|||..:.|..|::......|.:.||.|    ...|..:.::.|          ..|:
  Fly   589 LKEGVGKAGWRLGLQIVAALTALSFFMGLMYRPAS----LYHPQRRAIQHL----------KNQR 639

Human   244 GRTEEKDGGLGNEETLCDLQAQECPDQAGHRKNMCALRILKTVSWLTMRVRKGFEDWYSGYFGTA 308
            .:..||       :.:.....:..|     :.....:..||:|   |:::
  Fly   640 KKMREK-------KPILSQDVESTP-----KYFFLDISSLKSV---TVKI--------------- 674

Human   309 SLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVNLYNLSEQ----NDVFPLTSIIAIVHIFGKVI 369
                           |...||.....|:.|..:...|.:||    .::..|.:.:.|....|.||
  Fly   675 ---------------LLMTSSVASFGIYTPMFLMALNAAEQGSDVQELVLLQTFLGISMALGVVI 724

Human   370 LGVIADLPCISVWNVFLLANFTL-------------VLSIFILPLMHTYAGLAVICALIGFSSGY 421
            .|.:       :...|::.:|.:             .|:|..|..:..|.||.::..|.|...|.
  Fly   725 AGAL-------LRRCFVIRHFVINTKIVTQLFLSIVALAILFLSFVMGYTGLCILSWLYGIGLGG 782

Human   422 FSL-MPVVTEDLVGIEHLANAYGIIICANGISALLGPPFAGWIYDITQKYD-FSFYICGLLYMIG 484
            |.. :.::..:.:.::|.:.|:|.|.....:..|:..|...::.|.:.||. ..:|||.....|.
  Fly   783 FQYSLKILALERIKLKHFSKAWGFIRGVESVPVLISVPLTSFLNDYSLKYGRAGYYICSAAAAIS 847

Human   485 --ILFLLIQPCIRIIEQSRRKYMDGAH 509
              |:|.:.:|     :|..::.....|
  Fly   848 GIIIFFISEP-----QQQHQQQQQQLH 869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC16A14	NP_689740.2	MFS_MCT14	33..492	CDD:340987	103/479 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..255		5/40 (13%)
CG10019	NP_001368939.1	MFS_MCT_SLC16	444..840	CDD:340910	98/462 (21%)