Protein Alignment SLC16A14 and CG8051

DIOPT Version :10

• Sequence 1: NP_689740.2
• Gene: SLC16A14 / 151473
• HGNCID: 26417
• Length: 510
• Species: Homo sapiens
• Sequence 2: NP_573377.1
• Gene: CG8051 / 32925
• FlyBaseID: FBgn0031012
• Length: 616
• Species: Drosophila melanogaster
• Alignment Length: 582
• Identity: 114/582 - (19%)
• Similarity: 192/582 - (32%)
• Gaps: 183/582 - (31%)

Human     7 DIGYDFEDGPKDKKTLKPHPNIDGGWAWMMVLSSFFVHILI-----------MGSQMA-LGVLNV 59
            |:|.||         :.|    ||||.|::.::| .|:||:           ...:|| ||:.:.
  Fly    72 DLGEDF---------VAP----DGGWGWLVSVAS-GVNILVTFALAQQFGILFRDRMAGLGISSS 122

Human    60 EWLEEFHQSRGLTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVH 124
            |          ||..::: .:.::...|...|........|..|::|.::..||.....:|....
  Fly   123 E----------LTTIINT-QIAVSAFTGLLNGPLFRRYTYRVVALVGSVLTFLGLFWMVFADTFA 176

Human   125 YLFITFGVAAGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWR 189
            ...::|.:..|.|.|:....:.:.|..||:.:|..|........|.|..:......|:..|:|.:
  Fly   177 VYIMSFSILYGFGRGLTVSASSLAVNTYFKVKRRTATAFQFGVAGLGPIVCPYFATYMLYEFGVQ 241

Human   190 NAMLIQGAVSLNLCVCGALMRP-----------------LSPGKNPNDPGEKDVRG--------L 229
            ...|:....||:...|..:.:|                 :.|.....|..|..::.        |
  Fly   242 GTTLLFAGASLHTIACSLIYQPVKWHVVKRDRDAEALQQVQPLAEREDQDEDIIKNVVEPETPVL 306

Human   230 PA------HSTESVKSTGQQGR--TEEKDGGLGNEE----------------------------- 257
            |.      .|..|:.|.|.:.|  |.||....|:.|
  Fly   307 PRANDGWFGSRASLNSVGTRNRLNTWEKSDSNGHVELKRLSSKDSNPGRQLRSISVSHSIKEEEA 371

Human   258 ------------TLCDLQAQECPDQAGHRKNMCALRILKTVSWLTMRVRKGFEDWYSGYFGTASL 310
                        .|.:.:.||..|:...::.......:|.|.:..|.:.:...     |...|..
  Fly   372 TGYNSDHEVQHTELTEKEKQELEDEKERQRRKKLPFYMKVVIFFDMDLLRDIT-----YVNLAVG 431

Human   311 FTNRMFVAFIFWAL---------------------FAYSSFVIPFIHLPEIVNLYNLSEQNDVFP 354
            .|...||...|..|                     ..:...|:.|: :|.|....|||.:.
  Fly   432 ITLINFVEINFAILTPFILSDLGFNKDQIALAMSTLGFFDLVVRFL-IPLITAKINLSNRT---- 491

Human   355 LTSIIAIVHIFGKVILGVIADLPCISVWNVFLLANFTLVLSIF----------------ILPLMH 403
                     .|...|||:     ||....:.:.:||.::::||                |:|
  Fly   492 ---------FFVVGILGM-----CIGRMFLSMTSNFYVMMAIFLWLGLNKAFRTVFWSLIIP--- 539

Human   404 TYAGLAVICALIGFS---SGYFSLMPVVTEDLVGIEHLANAYGIIICANGISALLGPPFAGW 462
            :|..|..:.|..|..   ||.||:   :...|:|:.....:|.:.:  |.::||....||||
  Fly   540 SYVPLKRLPAAAGLQLLMSGTFSM---IFGPLIGLIRDHTSYAVTL--NLLNALCVMAFAGW 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC16A14	NP_689740.2	MFS_MCT14	33..492	CDD:340987	105/556 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..255		13/56 (23%)
CG8051	NP_573377.1	MFS_MCT_SLC16	85..599	CDD:340910	105/556 (19%)