Protein Alignment SLC16A14 and CG8034

DIOPT Version :10

• Sequence 1: NP_689740.2
• Gene: SLC16A14 / 151473
• HGNCID: 26417
• Length: 510
• Species: Homo sapiens
• Sequence 2: NP_573376.2
• Gene: CG8034 / 32924
• FlyBaseID: FBgn0031011
• Length: 647
• Species: Drosophila melanogaster
• Alignment Length: 644
• Identity: 135/644 - (20%)
• Similarity: 225/644 - (34%)
• Gaps: 172/644 - (26%)

Human    19 KKTLKPHPNIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFH-QSRGLTAWVSSLSMGI 82
            |:..|..|  ||||.|:.......|::.....:.:.|:|..:.|:|.: .:.|....:|:|.:.:
  Fly     4 KQPRKVAP--DGGWGWVACFGVSLVNLATRSIEPSFGLLFGDTLKELNVGTTGAAVIISALDVCM 66

Human    83 TLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVHYLFITFGVAAGLGSGMAYLPAVV 147
            . ..|.|:|..:.....|:.||.|.|:..||..|::.|.::.::..|:.|..|:|.|::...|.|
  Fly    67 N-FSGLFVGPLLKEFSYRKVAIAGSLLCGLGLALTSPATSMAHILSTYSVINGIGVGLSTSAAFV 130

Human   148 MVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMLIQGAVSLNLCVCGALMRPL 212
            .:..||:.:|..|.|||..||..|..:|..|::.|...|.:|.|:|:...|:||..|...|::|:
  Fly   131 ALNHYFKHKRGQAVGLSMAGTAMGMLIMPQLVRILLEAYDFRGAVLLLAGVALNATVGSVLLQPV 195

Human   213 S------------------PGKNP----------------------NDPGEKDVRGLPAHST--- 234
            .                  |...|                      .|..|:|  .||..:|
  Fly   196 KWHMKEEFDDEELMCISALPTPQPQLTVGGAGGAASAGAPVFKVIKEDGNEED--ALPEMNTLLF 258

Human   235 -------ESVKSTGQQGRTEEKDG---GLGNEETLCDLQAQECPDQAGH-------------RKN 276
                   .|::....:......:|   |:....|...:.:......|.|             ..|
  Fly   259 HKPHPHQHSMRKNYSEMAMNTMNGSRLGIPKRPTFPRIMSLAGVQSAAHGAGGDSGGYTSQAEVN 323

Human   277 MCALRILK------------TVSWLTMRVRKGFEDWYSG-----YFGTAS--------------- 309
            ...||..|            |.|.|.:.:..|.:::...     ..|||:
  Fly   324 ATQLRCRKASVTSNLSYMDFTGSILQVHLNTGDDEFEQNDRELRRVGTATGSIVLGGHRDSFIKM 388

Human   310 --------------------------------------------LFTNRMFVAFIFWALFAYSSF 330
                                                        :|.|.:|...||:........
  Fly   389 KPTELDKQAEAAAALDEEAKKKAKKPGFWRRFADLLDIDMLKDKMFLNLLFGLSIFYVAEMNFKM 453

Human   331 VIPFIHLPEIVNLYNLS-EQNDVFPLTSIIAIVHIFGKVILGVIADLPCISVWNVFLLANFTLVL 394
            |.||.       ..||. ::.||....||.||..|..:::|..|.|...|....:||::...:.|
  Fly   454 VTPFF-------FANLGYQKTDVAFCLSITAITDIAARIVLPPIFDRTTIKKRTIFLVSIIFVAL 511

Human   395 SIFILPLMHTYAGLAVICALIGFSSG-YFSLMPVVTEDLVGIEHLANAYGIIICANGISALLGPP 458
            :..|:.....:..|.:..::.||..| ..|...:...:...:|.|.:|:|..:....:..:...|
  Fly   512 TRSIMAEQTEWTQLMIWLSICGFFRGSALSNFTLTVSEYCSLEKLPSAFGWHLVGKALFVITFGP 576

Human   459 FAGWIYDITQKYDFSFYICGLLYMI-----GILFLLIQPCIRIIE--QSRRKYMDGAHV 510
            ..|.|.|:|..|....:...:..||     ||.:|        :|  ||||:..|.|.:
  Fly   577 LIGLIRDVTDSYPICIHTQSVCIMICATAWGIEYL--------VEYIQSRRRTADAAQL 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC16A14	NP_689740.2	MFS_MCT14	33..492	CDD:340987	121/608 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..255		11/75 (15%)
CG8034	NP_573376.2	MFS	16..>193	CDD:475125	50/177 (28%)
		MFS	<428..609	CDD:475125	43/187 (23%)