Protein Alignment SLC16A14 and CG8028

DIOPT Version :10

• Sequence 1: NP_689740.2
• Gene: SLC16A14 / 151473
• HGNCID: 26417
• Length: 510
• Species: Homo sapiens
• Sequence 2: NP_001097031.2
• Gene: CG8028 / 32923
• FlyBaseID: FBgn0031010
• Length: 563
• Species: Drosophila melanogaster
• Alignment Length: 541
• Identity: 120/541 - (22%)
• Similarity: 205/541 - (37%)
• Gaps: 86/541 - (15%)

Human    29 DGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMGITLIVGPFIGLF 93
            ||||..::.:.........:.:..:.|::..|:|:.........|.::|.........|.|.|..
  Fly    35 DGGWGILVCIGMALPFTSALAALPSFGLVFGEFLKSIGAETSAMAIITSAFFSSMSFAGLFSGSL 99

Human    94 INTCGCRQTAIIGGLVNSLGWVLSAYAANVHYLFITFGVAAGLGSGMAYLPAVVMVGRYFQKRRA 158
            ....|.||..:.||::..||..:..:|.:..:|.:.|.|..|...|:...........||.|.|.
  Fly   100 FQRFGMRQVGVTGGILYFLGTGMQLFATSTLHLIMAFSVVQGFAFGLMVPTCYTTFNHYFVKNRV 164

Human   159 LAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMLIQGAVSLNLCVCGAL--------------- 208
            :....:.|..|.|:.|..::::.|.:.||:|..:||...::.: .|.|.|
  Fly   165 MWMSFAQTLIGLGSMLYPIVMQKLMSWYGFRGCLLILTGLNAH-AVFGMLVMHPVEWHMRRVPIQ 228

Human   209 ------MRPLSP---------------GKNPN----DPGEKDVRGLPAHSTE-----------SV 237
                  ::.|||               .:.||    |||.:.:    :|:.|           |:
  Fly   229 PEEQEELKELSPTVVIRVQPETPLKATREEPNFHTADPGARKL----SHAEEQMLKVLSSRASSI 289

Human   238 KSTGQ-QGRTEEKDGGLGNEETLCDLQAQECPDQAGHRKNMCALRILKTVSWLTMRVRKGFEDWY 301
            .|.|. .|.....|   .:.:.:..||....|..........|.......||  :|....|.|
  Fly   290 TSLGNWSGPVVVSD---ASPQMMHSLQTSRRPSTIAGASGAVAPAHATKKSW--VRTIVDFLD-- 347

Human   302 SGYFGTASLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVNLYNLS-EQNDVFPLTSIIAIVHIF 365
                  .:|....:||..:....||..|.:..|...|  |.|:.|. .:.|...:.:|.|...:.
  Fly   348 ------LTLLKKPIFVNIVLGITFALYSDITFFTMQP--VYLFELGYSRPDTATIIAIGAAADLA 404

Human   366 GKVILGVIADLPCISVWN--VFLLANFTLVLSIFILPLMHTYAGLAVICALIGFSSGYFSL-MPV 427
            .::.|.:.|  .||.|.:  ::|......|.:.|....:..:.|:|.|.|:|||...:..: :|:
  Fly   405 SRIFLAITA--VCIQVPSRYIYLAGAVFTVFARFAFNGITQFVGMACITAVIGFLRTWLHVPLPL 467

Human   428 VTEDLVGIEHLANAYGIIICANGISALLGPPFAGWIYDITQKYDFSFYICGLLYMIGILFLLIQP 492
            |..|.:..|..|..||:.:...|.:..|..|..|:|.|.|:.|.|.|:|     :.|.:.|...|
  Fly   468 VFADYLPKERFATGYGLFMFIQGNAMFLIGPIVGFIRDKTRDYIFVFHI-----LNGFMILCAAP 527

Human   493 C---IRIIEQSRRKYMDGAHV 510
            .   :.|::..||..::..:|
  Fly   528 WVLEVLIVKFRRRNKIERNNV 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC16A14	NP_689740.2	MFS_MCT14	33..492	CDD:340987	111/514 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..255		13/71 (18%)
CG8028	NP_001097031.2	MFS_MCT_SLC16	39..531	CDD:340910	112/518 (22%)