Protein Alignment SLC16A14 and CG14196

DIOPT Version :10

• Sequence 1: NP_689740.2
• Gene: SLC16A14 / 151473
• HGNCID: 26417
• Length: 510
• Species: Homo sapiens
• Sequence 2: NP_573367.1
• Gene: CG14196 / 32915
• FlyBaseID: FBgn0031002
• Length: 600
• Species: Drosophila melanogaster
• Alignment Length: 612
• Identity: 134/612 - (21%)
• Similarity: 232/612 - (37%)
• Gaps: 149/612 - (24%)

Human     2 YTSHE--DIGYDFEDGPKDKKTLKPHPNIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEE 64
            |..|:  |:|.||         :.|    |.||||::.:::...::.|.......|.|..|.|.:
  Fly    22 YNKHDKSDLGDDF---------VAP----DAGWAWIVCVAAGVSNLSIYPCLQQFGFLFRERLSD 73

Human    65 FHQSRG-LTAWVS---SLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVHY 125
            ...|.. :||.::   ::|....|:.||....|.    .||.|:.|.|:.|...:|:|:......
  Fly    74 LGMSSSQITAIINANPAVSACTGLLNGPMFRRFT----FRQVAMAGSLLISGSLILTAFCETFLS 134

Human   126 LFITFGVAAGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRN 190
            ..:.:.:..|.|.|::...:.:.:..||||:|..|.|.|.|.||.|...:..|:.:|...||.:.
  Fly   135 YMVAYALLFGFGMGISVSASSLAINTYFQKKRRRAAGFSWTITGLGPIFLPHLVTFLLTIYGVQG 199

Human   191 AMLIQGAVSLNLCVCGALMRP----LSPGKNPNDPGEKDVRGLPAHSTESVKSTGQQGRTEEKDG 251
            ..|:..|:||:..||..:.:|    :.|........|:....|.||      .:.||.|   :.|
  Fly   200 TTLLFAAISLHSFVCALIYQPVRYHVKPPVEQLADQEQQAEALCAH------CSWQQKR---EPG 255

Human   252 GLGNEETLC------------------------------------------------DL---QAQ 265
            |:.:.:.||                                                ||   |..
  Fly   256 GIFSSQYLCQDDDAQRPGYEICEPGTPMLSRANDGWYGSRLSLTSGRLRFRTISSSKDLEQTQRL 320

Human   266 ECP--DQAGHRKN--------------------MCALRILKTVSWLTMRVRKGFEDWYSGYFGTA 308
            .||  ::..|..:                    :|.....|.......|..|..|...:| ..:|
  Fly   321 HCPISEEQNHESDEFLRPNNFRRERVESNLEAKLCCQCSAKREEHNNNRKEKEAEAEEAG-MESA 384

Human   309 SLFTNRM-FVAFI--FWALFAYSSFVIPFIHLPEIVNLYNLSEQNDVFPLTSIIAIVHIFG---- 366
            .|...:| |:|.:  |:.|.....|.  |::|...:.:.|..|.|  |.:.:...:|. ||
  Fly   385 PLHDPQMSFLAKVVTFFDLDLLRDFT--FVNLVAGLTIINFGELN--FSILTPFILVD-FGFDTP 444

Human   367 --KVILGVIADL--------PCIS---VWN---VFLLANFTLVLSIFILPLMHTYAGLAVICAL- 414
              .:.:.::|.|        |.::   .|:   .||:....:.|...::....:|:  .::|:.
  Fly   445 QITLAMSLLAGLDITMRFMVPFLTEKIPWDNRVFFLIGVVGIALGRTVVACTRSYS--LILCSFV 507

Human   415 -IGFSSGYFSLM-PVVTEDLVGIEHLANAYGIIICANGISALLGPPFAGWIYDITQKYDFSFYI- 476
             ||...|..::. |::....|.:..|..|.|:.:..:|:..|:|.||.|.:.|   :||:|..:
  Fly   508 WIGLCKGVRTIFWPLIIPGYVPLNRLPGASGLQLLISGLFTLIGGPFVGLVRD---RYDYSVTLH 569

Human   477 CGLLYMIGILFLLIQPCIRIIEQSRRK 503
            |  |.|:..:.........:|.:.|||
  Fly   570 C--LNMMSFVAATSWSLEALIRRHRRK 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC16A14	NP_689740.2	MFS_MCT14	33..492	CDD:340987	120/566 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..255		10/40 (25%)
CG14196	NP_573367.1	MFS_MCT_SLC16	42..585	CDD:340910	120/568 (21%)