Protein Alignment CTSK and CG5367

DIOPT Version :9

• Sequence 1: NP_000387.1
• Gene: CTSK / 1513
• HGNCID: 2536
• Length: 329
• Species: Homo sapiens
• Sequence 2: NP_609387.1
• Gene: CG5367 / 34401
• FlyBaseID: FBgn0032228
• Length: 338
• Species: Drosophila melanogaster
• Alignment Length: 311
• Identity: 115/311 - (36%)
• Similarity: 179/311 - (57%)
• Gaps: 17/311 - (5%)

Human    24 THWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQ 88
            :.:|.:|..:.::|....||:.....:|:|.|.|..||.....|..::.|..|...||:::..::
  Fly    34 SEFEKFKNNNNRKYLRTYDEMRSYKAFEENFKVIEEHNQNYKEGQTSFRLKPNIFADMSTDGYLK 98

Human    89 K-MTGLKVPLSHSRSNDTLYIPEWEG-----RAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGA 147
            . :..||..:..|..|    :.|..|     ..|:|:|:|.||::||..||..||||:|||...:
  Fly    99 GFLRLLKSNIEDSADN----MAEIVGSPLMANVPESLDWRSKGFITPPYNQLSCGSCYAFSIAES 159

Human   148 LEGQLKKKTGKLLNLSPQNLVDC-VSE-NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESC 210
            :.||:.|:|||:|:||.|.:||| ||. |.||.||.:.|...|:|...||..:..||||.::..|
  Fly   160 IMGQVFKRTGKILSLSKQQIVDCSVSHGNQGCVGGSLRNTLSYLQSTGGIMRDQDYPYVARKGKC 224

Human   211 MYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLN 275
            .:.|.........:..:|..:|:|::.||..:|||:::|:||..:||.||.|:|.|..|:|.::|
  Fly   225 QFVPDLSVVNVTSWAILPVRDEQAIQAAVTHIGPVAISINASPKTFQLYSDGIYDDPLCSSASVN 289

Human   276 HAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASF 326
            ||::.:|:    |..:||:||.||:|||..|||.: |...|.|||||.|::
  Fly   290 HAMVVIGF----GKDYWILKNWWGQNWGENGYIRI-RKGVNMCGIANYAAY 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CTSK	NP_000387.1	Inhibitor_I29	26..85	CDD:214853	16/58 (28%)
		Peptidase_C1	115..327	CDD:306594	93/214 (43%)
CG5367	NP_609387.1	Inhibitor_I29	36..96	CDD:285458	16/59 (27%)
		Peptidase_C1A	128..336	CDD:239068	93/213 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.830