Protein Alignment ZNF385B and znf385b

DIOPT Version :9

• Sequence 1: NP_001339738.1
• Gene: ZNF385B / 151126
• HGNCID: 26332
• Length: 532
• Species: Homo sapiens
• Sequence 2: XP_021334290.1
• Gene: znf385b / 368405
• ZFINID: ZDB-GENE-030616-154
• Length: 532
• Species: Danio rerio
• Alignment Length: 579
• Identity: 320/579 - (55%)
• Similarity: 378/579 - (65%)
• Gaps: 100/579 - (17%)

Human     1 MRYSLSPDNHLEDGIMNMANFLRG-FEEKGIKNDRPEDQLSKEKKKILFSFCEVCNIQLNSAAQA 64
            |:..|||...:|:|.:..|  :.| .|.|...|...:.||.:||||:|:|.|:||||||:|||||
Zfish     7 MKTPLSPTQLIENGQLCFA--IPGCVEVKEPTNANVDMQLQQEKKKLLYSLCDVCNIQLHSAAQA 69

Human    65 QVHSNGKSHRKRVKQLSDGQ-PPPPAQASPSSNSSTDNQGWSQVSVALCIILVTYWKFCLSNLVA 128
            |||.|||||.||||||::|: |...|..:|:|..|.
Zfish    70 QVHYNGKSHLKRVKQLNNGEVPKASASLAPTSLQSL----------------------------- 105

Human   129 LEAGESPARMWSGLPSRGSTCHTTTLPALVRTPTLMMQPSLDIKPFMSFPVDSSSAVGLFPNFNT 193
                       |...|:||:||:.|||.|||||:||||..||:||||:|||:|||.|||||||||
Zfish   106 -----------SSSSSQGSSCHSNTLPTLVRTPSLMMQSGLDMKPFMTFPVESSSPVGLFPNFNT 159

Human   194 MDPVQKAVINHTFGVSIPPKKKQVISCNVCQLRFNSDSQAEAHYKGSKHAKKVKALDATKNKPKM 258
            ||||||||||||||||||||||||||||:|||||||||||||||||||||||:||.::.|||.|.
Zfish   160 MDPVQKAVINHTFGVSIPPKKKQVISCNICQLRFNSDSQAEAHYKGSKHAKKLKAQESPKNKQKS 224

Human   259 VPSKDS------------AKANPSCSITPITGNNSDKSEDK------GKLKAS------------ 293
            ..::||            .....:.|.|.:|.:.||::|..      .|:.||
Zfish   225 AVAQDSGTKTITSTSTNTTTTTTTSSCTAVTASCSDQTEKSTEPLAAHKVPASPQAFVPAPVAPA 289

Human   294 -------------SSSQPSSSESGSFLLKSGTTPLPPGAATSPSKSTNGAPGTVVESEEEKAKKL 345
                         .:|.|:.....:..||:  |..|....|:||:.:       |||||||||||
Zfish   290 VALVPSPCKTAPVHASPPTEPTGLAVALKN--TSKPAALPTAPSEPS-------VESEEEKAKKL 345

Human   346 LYCSLCKVAVNSLSQLEAHNTGSKHKTMVEARNGAGPIKSYPRPGSRLKMQ--NGSKGSGLQNKT 408
            ||||||||||||||||||||||||||||:||||||||||:||||||:||:|  ..:|||||||||
Zfish   346 LYCSLCKVAVNSLSQLEAHNTGSKHKTMLEARNGAGPIKAYPRPGSKLKVQATQLNKGSGLQNKT 410

Human   409 FHCEICDVHVNSEIQLKQHISSRRHKDRVAGKPLKPKYSPYNKLQRSPSILAAKLAFQKDMMKPL 473
            |||||||||||||||||||||||||||||||||.|||||||||.|||.|.||||||.|.|::||:
Zfish   411 FHCEICDVHVNSEIQLKQHISSRRHKDRVAGKPTKPKYSPYNKQQRSSSSLAAKLALQNDLVKPI 475

Human   474 APAFLSSPLAAAAAVSSALSLPPRPSASLFQAPAIPPALLRPGHGPIRATPASILFAPY 532
            :||||.||.:.....|  :||.|||:.|:||..::|.:.||...||||.|..|||||||
Zfish   476 SPAFLPSPFSTTTVPS--ISLHPRPNTSIFQTASLPHSFLRAAPGPIRPTTGSILFAPY 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZNF385B	NP_001339738.1	ZnF_U1	50..80	CDD:197732	24/29 (83%)
		C2H2 Zn finger	220..242	CDD:275371	20/21 (95%)
		zf-met	220..242	CDD:315537	20/21 (95%)
		zf-met	346..370	CDD:315537	23/23 (100%)
		C2H2 Zn finger	348..410	CDD:275371	54/63 (86%)
		zf-met	409..433	CDD:315537	23/23 (100%)
		C2H2 Zn finger	411..433	CDD:275371	21/21 (100%)
znf385b	XP_021334290.1	ZnF_U1	56..85	CDD:197732	24/28 (86%)
		C2H2 Zn finger	186..208	CDD:275371	20/21 (95%)
		zf-met	186..208	CDD:315537	20/21 (95%)
		zf-met	346..370	CDD:315537	23/23 (100%)
		C2H2 Zn finger	348..370	CDD:275371	21/21 (100%)
		zf-met	411..435	CDD:315537	23/23 (100%)
		C2H2 Zn finger	413..435	CDD:275371	21/21 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C194324311
Domainoid	1	1.000	151	1.000	Domainoid score	I17795
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H17606
Inparanoid	1	1.050	568	1.000	Inparanoid score	I5640
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG41275
OrthoDB	1	1.010	-	-		D286103at7742
OrthoFinder	1	1.000	-	-		FOG0011867
OrthoInspector	1	1.000	-	-		otm28307
orthoMCL	1	0.900	-	-		OOG6_111634
Panther	1	1.100	-	-	LDO	PTHR23067
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R11845
SonicParanoid	1	1.000	-	-		X9681
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	1	1.500	-	-
	16	16.440