DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hao1 and CG18003

DIOPT Version :9

Sequence 1:	NP_034533.1	Gene:	Hao1 / 15112	MGIID:	96011	Length:	370	Species:	Mus musculus
Sequence 2:	NP_001027401.1	Gene:	CG18003 / 3771779	FlyBaseID:	FBgn0061356	Length:	366	Species:	Drosophila melanogaster

Alignment Length:	357	Identity:	173/357 - (48%)
Similarity:	248/357 - (69%)	Gaps:	3/357 - (0%)

- Green bases have known domain annotations that are detailed below.

Mouse     5 LVCISDYEQHVRSVLQKSVYDYYRSGANDQETLADNIQAFSRWKLYPRMLRNVADIDLSTSVLGQ 69
            |||:.|:|:.....|:|:..|||||||.:|.||..|.:||.|.:|.||.||:|:.:|:||.:.|:
  Fly     3 LVCVEDFEKKAVGQLEKNALDYYRSGAGEQFTLGLNREAFRRLRLRPRCLRDVSRLDISTKIFGE 67

Mouse    70 RVSMPICVGATAMQCMAHVDGELATVRACQTMGTGMMLSSWATSSIEEVAEAGPEALRWMQLYIY 134
            ::..|:.:..||||.|||.|||:...||....|:..:||:.:|:|:|::|...|:.::|.|||||
  Fly    68 QMQWPLGIAPTAMQKMAHPDGEVGNARAAGKAGSIFILSTLSTTSLEDLAAGAPDTIKWFQLYIY 132

Mouse   135 KDREISRQIVKRAEKQGYKAIFVTVDTPYLGNRIDDVRNRFKLPPQLRMKNFETNDLAFSPKGNF 199
            |||.|:.::|:||||..:||:.:|:|.|..|:|..||||.|.||..|.:.||:  .:..:..||.
  Fly   133 KDRTITEKLVRRAEKANFKALVLTIDAPIFGHRRADVRNNFSLPSHLSLANFQ--GVKATGVGNA 195

Mouse   200 G-DNSGLAEYVAQAIDPSLSWDDITWLRRLTSLPIVVKGILRGDDAKEAVKHGVDGILVSNHGAR 263
            . ..||:.|||:...||:::|.||.||:.:|.|||||||:|..:||..|.:.|..|::|||||||
  Fly   196 AMGASGINEYVSSQFDPTITWKDIAWLKGITHLPIVVKGVLTAEDAVLAQEFGCAGLIVSNHGAR 260

Mouse   264 QLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIIWGLAFQGEKG 328
            |:|.|||:|:.|||||:||...:.|.||||:.:|.|:.||||||||.||||||.:||||:.|:||
  Fly   261 QIDTVPASIEALPEIVKAVGDNLVVMLDGGIMQGNDIFKALALGAKTVFVGRPAVWGLAYNGQKG 325

Mouse   329 VQDVLEILKEEFRLAMALSGCQNVKVIDKTLV 360
            |:::|.:|:::|...|||.||||:..|...:|
  Fly   326 VEEMLSVLRKDFETTMALIGCQNLGDITSAMV 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hao1	NP_034533.1	alpha_hydroxyacid_oxid_FMN	9..357	CDD:239203	169/348 (49%)
		FMN_dh	16..362	CDD:279418	168/346 (49%)
		Microbody targeting signal. /evidence=ECO:0000255	368..370
CG18003	NP_001027401.1	alpha_hydroxyacid_oxid_FMN	7..353	CDD:239203	168/347 (48%)
CG18003	NP_001027401.1	FMN_dh	17..359	CDD:279418	168/343 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830671
Domainoid	1	1.000	344	1.000	Domainoid score	I1056
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6578
Inparanoid	1	1.050	355	1.000	Inparanoid score	I2229
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54906
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001123
OrthoInspector	1	1.000	-	-		oto92206
orthoMCL	1	0.900	-	-		OOG6_100930
Panther	1	1.100	-	-	LDO	PTHR10578
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1926
SonicParanoid	1	1.000	-	-		X693
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.930