Protein Alignment Hand2 and twi

DIOPT Version :9

• Sequence 1: NP_034532.3
• Gene: Hand2 / 15111
• MGIID: 103580
• Length: 217
• Species: Mus musculus
• Sequence 2: NP_001033967.1
• Gene: twi / 37655
• FlyBaseID: FBgn0003900
• Length: 490
• Species: Drosophila melanogaster
• Alignment Length: 181
• Identity: 59/181 - (32%)
• Similarity: 84/181 - (46%)
• Gaps: 44/181 - (24%)

Mouse     8 PH---HPVVH--------HEGYPFAAAAAAAAAAAASRCSHEENPYF-HGWLIGHPEMSPPDYSM 60
            ||   |..:|        .|||..|.:...:|.:::.|   ::..|. |..|....:::....|.
  Fly   256 PHQQSHAQMHFQNAYRQSFEGYEPANSLNGSAYSSSDR---DDMEYARHNALSSVSDLNGGVMSP 317

Mouse    61 ALSYSPEYASGAAG--LDHSHYGGVPPGAGPPGLGGPR------PVK---------RRGTANRKE 108
            |....    .|:||  ||.|..||       .....||      |.|         :|..||.:|
  Fly   318 ACLAD----DGSAGSLLDGSDAGG-------KAFRKPRRRLKRKPSKTEETDEFSNQRVMANVRE 371

Mouse   109 RRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLAKDD 159
            |:||||:|.||..|::.||.:|:| |||||:||:|||.||.:|..:|:..|
  Fly   372 RQRTQSLNDAFKSLQQIIPTLPSD-KLSKIQTLKLATRYIDFLCRMLSSSD 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hand2	NP_034532.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	76..116		17/54 (31%)
		bHLH_TS_HAND2	100..161	CDD:381477	32/60 (53%)
twi	NP_001033967.1	HLH	363..413	CDD:278439	29/50 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839647
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5507
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.830