DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hand1 and Fer1

DIOPT Version :9

Sequence 1:	NP_032239.1	Gene:	Hand1 / 15110	MGIID:	103577	Length:	216	Species:	Mus musculus
Sequence 2:	NP_001262334.1	Gene:	Fer1 / 2768661	FlyBaseID:	FBgn0037475	Length:	256	Species:	Drosophila melanogaster

Alignment Length:	131	Identity:	42/131 - (32%)
Similarity:	67/131 - (51%)	Gaps:	23/131 - (17%)

- Green bases have known domain annotations that are detailed below.

Mouse    74 PDARPSQSPGRLEALGSRLPKRKGSGPKKERRRTESINSAFAELRECIPNVPADTKLSKIKTLRL 138
            |.:|.|..|.||:. .|::.:::.:...:||||.:|||.||..||..||.:|.:.:|||:.||:|
  Fly    67 PFSRRSHKPRRLKC-ASQMAQQRQAANLRERRRMQSINEAFEGLRTHIPTLPYEKRLSKVDTLKL 130

Mouse   139 ATSYIAYLMDVLAKDAQAGDPEAFKAELKKTDGGRESKRKRELPQQPESFPPASGPGEKRIKGRT 203
            |.|||.:|.:::.||....:|..              ..:|...::|        |.:..:|.||
  Fly   131 AISYITFLSEMVKKDKNGNEPGL--------------SLQRNYQKEP--------PKKIILKDRT 173

Mouse   204 G 204
            |
  Fly   174 G 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hand1	NP_032239.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	53..109		11/34 (32%)
		HLH	103..152	CDD:197674	25/48 (52%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	165..203		4/37 (11%)
Fer1	NP_001262334.1	HLH	92..144	CDD:197674	25/51 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810