Protein Alignment PNPLA5 and bmm

DIOPT Version :10

• Sequence 1: NP_620169.1
• Gene: PNPLA5 / 150379
• HGNCID: 24888
• Length: 429
• Species: Homo sapiens
• Sequence 2: NP_001163445.1
• Gene: bmm / 39611
• FlyBaseID: FBgn0036449
• Length: 553
• Species: Drosophila melanogaster
• Alignment Length: 188
• Identity: 34/188 - (18%)
• Similarity: 55/188 - (29%)
• Gaps: 66/188 - (35%)

Human     5 LWMGDLEPYMDE---NFISR--AFATMGETVMSVKIIRNRLTGIPAGYCFVEFADL----ATAEK 60
            :|:|....|.|:   ..:.|  .|..||.:|.:               ..||..:|    |:.:|
  Fly   105 VWLGRTGIYKDKERAEILGRISLFCWMGSSVCT---------------SLVEVGELGRLSASIKK 154

Human    61 CLHKINGKPLPGATPAKRFKLNYATYGKQPDNSPEYSLFVGDLTPDVDDGMLYEFFVKVYPSCRG 125
            ...:|..|.          |.....|..:.:.|.|.||.:      :..||
  Fly   155 LEKEIGNKD----------KHQNEQYRAKVEKSNERSLAL------IKAGM-------------- 189

Human   126 GKVVLDPTGVSKGYGFVKFTDELEQKRALTECQGAVGLGCKPVRLSVAIPKASRVKPV 183
                    .|...:|.:    :|..|:......||.|.....:.....:|...:.|.|
  Fly   190 --------DVVVAFGLL----QLAPKKVTPRVTGAFGFASSLISCYQLLPSHPKSKMV 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PNPLA5	NP_620169.1	Pat_PNPLA5-mammals	1..405	CDD:132862	34/188 (18%)
		GXGXXG. /evidence=ECO:0000255|PROSITE-ProRule:PRU01161	16..21		0/7 (0%)
		GXSXG. /evidence=ECO:0000255|PROSITE-ProRule:PRU01161	47..51		0/3 (0%)
		DGA/G. /evidence=ECO:0000255|PROSITE-ProRule:PRU01161	168..170		0/1 (0%)
bmm	NP_001163445.1	Pat_iPLA2	1..245	CDD:132857	34/188 (18%)