Protein Alignment DUSP18 and MKP-4

DIOPT Version :10

• Sequence 1: NP_689724.3
• Gene: DUSP18 / 150290
• HGNCID: 18484
• Length: 188
• Species: Homo sapiens
• Sequence 2: NP_608332.2
• Gene: MKP-4 / 32963
• FlyBaseID: FBgn0031044
• Length: 387
• Species: Drosophila melanogaster
• Alignment Length: 137
• Identity: 43/137 - (31%)
• Similarity: 73/137 - (53%)
• Gaps: 7/137 - (5%)

Human    20 LSQITKSLYISNGVAANNKLMLSSNQITMVINV-SV----EVVNTLYEDIQYMQVPVADSPNSRL 79
            :.::...|::.|..||.:...|.|.:||.::.: ||    .::...:...:|:|  :||.|...:
  Fly    39 IDEVDTGLFLGNLTAATHMETLRSFKITHILTLDSVPLPQHILEASFLTTKYIQ--IADMPREDI 101

Human    80 CDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRPIIRPN 144
            ....:...|.|.|...:||..|:||..|||||::..:||:||.|.:..|.|:...|:.|..::||
  Fly   102 LQHLEGCVDFISSALAQQGNVLVHCYFGVSRSSSTVIAYMMKRHNLDFLPAYELVKAKRRFVQPN 166

Human   145 SGFWEQL 151
            :||..||
  Fly   167 AGFVSQL 173

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DUSP18	NP_689724.3	DUSP18_21	19..176	CDD:350421	43/137 (31%)
MKP-4	NP_608332.2	DSP	39..175	CDD:350348	43/137 (31%)